Michele Tomasicchio

All papers authored by Michele Tomasicchio

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2024 Charnay van der Merwe, Michele Tomasicchio

, Shameem Jaumdally, Lindsay Wilson, Andrea Kotze, Lynn Semple, Stuart Meier, Anil Pooran, Carley Mandviwala, Aliasgar Esmail, Jessica Burns, Rolanda Londt, Komala Pillay, Malika Davids, Riyaadh Roberts and 21 other authors

SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset

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2023 Khelan R. Dheda, Chad M. Centner, Lindsay Wilson, Anil Pooran, Shireen Grimwood, Yonas T. Ghebrekristos, Suzette Oelofse, Ivan A. Joubert, Aliasgar Esmail, Michele Tomasicchio

Intensive Care Unit Sluice Room Sinks as Reservoirs and Sources of Potential Transmission of Carbapenem-Resistant Bacteria in a South African Tertiary Care Hospital

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Aliasgar Esmail, Philippa Randall, Suzette Oelofse, Michele Tomasicchio

, Anil Pooran, Richard Meldau, Edson Makambwa, Lynelle Mottay, Shameem Jaumdally, Gregory Calligaro

, Stuart Meier, Marianna de Kock, Tawanda Gumbo, Robin Mark Warren, Keertan Dheda

Comparison of two diagnostic intervention packages for community-based active case finding for tuberculosis: an open-label randomized controlled trial

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2022 Alexis J. Bick

, Chanel Avenant

, Michele Tomasicchio

, Zephne van der Spuy

, Janet P. Hapgood

Increased HIV‐1 infection in PBMCs treated in vitro with menstrual cycle phase hormones or medroxyprogesterone acetate likely occurs via different mechanisms

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Xiyuan Bai, An Bai, Michele Tomasicchio

, James R. Hagman

, Ashley M. Buckle

, Arnav Gupta

, Vineela Kadiyala, Shaun Bevers

, Karina A. Serban, Kevin Kim

, Zhihong Feng, Kathrin Spendier

, Guy Hagen, Lorelenn Fornis, David E. Griffith and 4 other authors

α1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages

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Aliasgar Esmail

, Suzette Oelofse, Carl Lombard, Rubeshan Perumal, Linda Mbuthini, Akhter Goolam Mahomed, Ebrahim Variava, John Black, Patrick Oluboyo, Nelile Gwentshu, Eric Ngam, Tertius Ackerman, Linde Marais, Lynelle Mottay, Stuart Meier and 9 other authors

An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study)

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2021 Malika Davids, Anil Pooran, Liezel Smith, Michele Tomasicchio

, Keertan Dheda

The Frequency and Effect of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients With Tuberculosis: A Preliminary Report

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This paper was not found in any repository, but could be made available legally by the author.

Ina Schim van der Loeff, Merryn Voysey, Sue Ann Costa Clemens, Sue Ann Costa Clemens, Shabir A. Madhi, Lily Y. Weckx, Pedro M. Folegatti

, Parvinder K. Aley, Brian Angus, Vicky L. Baillie

, Shaun L. Barnabas, Qasim E. Bhorat, Sagida Bibi, Carmen Briner, Catherine M. Green and 782 other authors

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

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2020 Ina Schim van der Loeff, Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi, Lily Y. Weckx, Catherine M. Green, Pedro M. Folegatti

, Parvinder K. Aley, Brian Angus, Vicky L. Baillie

, Shaun L. Barnabas, Qasim E. Bhorat, Sagida Bibi, Carmen Briner, Paola Cicconi and 779 other authors

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

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Aliasgar Esmail, Anil Pooran, Natasha F. Sabur, Mohammed Fadul, Mantaj S. Brar, Suzette Oelofse, Michele Tomasicchio

, Keertan Dheda

An Optimal Diagnostic Strategy for Tuberculosis in Hospitalized HIV-Infected Patients Using GeneXpert MTB/RIF and Alere Determine TB LAM Ag

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Aliasgar Esmail, Michele Tomasicchio

, Richard Meldau, Edson Makambwa, Keertan Dheda

Comparison of Xpert MTB/RIF (G4) and Xpert Ultra, including trace readouts, for the diagnosis of pulmonary tuberculosis in a TB and HIV endemic setting

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Malika Davids, Anil Pooran, Clemens Hermann, Lynelle Mottay, Fawziyah Thompson, Jacob Cardenas, Jinghua Gu, Thearith Koeuth, Richard Meldau, Jason Limberis

, Phindile Gina, Shashikant Srivastava, Bridget Calder, Aliasgar Esmail, Michele Tomasicchio

and 3 other authors

A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin

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Michele Tomasicchio

, Jason Limberis

, Ruben van der Merwe, Rachael Jacobson, Richard Meldau, Grant Theron, Mark Nicol, Rob Warren, Keertan Dheda

Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region

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2019 Roslyn M. Ray, Michelle F. Maritz, Chanel Avenant, Michele Tomasicchio

, Sigcinile Dlamini, Zephne van der Spuy, Janet P. Hapgood

The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations

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2018 Michele Tomasicchio

, Malika Davids, Anil Pooran, Grant Theron, Liezel Smith, Lynn Semple, Richard Meldau, Janet Patricia Hapgood, Keertan Dheda

The Injectable Contraceptive Medroxyprogesterone Acetate AttenuatesMycobacterium tuberculosis–Specific Host Immunity Through the Glucocorticoid Receptor

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Michele Tomasicchio

, Lynn Semple, Aliasgar Esmail, Richard Meldau, Philippa Randall, Anil Pooran, Malika Davids, Lydia Cairncross, David Anderson, Jennifer Downs, Francois Malherbe, Nicolas Novitzky, Eugenio Panieri, Suzette Oelofse, Rolanda Londt and 2 other authors

An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells

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Michelle F. Maritz, Roslyn M. Ray, Alexis J. Bick, Michele Tomasicchio

, John G. Woodland, Yashini Govender, Chanel Avenant, Janet P. Hapgood

Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels

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2017 Gregory L. Calligaro

, Lynn S. Zijenah, Jonathan G. Peter, Grant Theron, Virginia Buser, Ruth McNerney, Wilbert Bara, Tsitsi Bandason, Ureshnie Govender, Michele Tomasicchio

, Liezel Smith, Bongani M. Mayosi, Keertan Dheda

Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial

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2016 Michele Tomasicchio

, Grant Theron, Elize Pietersen, Elizabeth Streicher

, Danielle Stanley-Josephs, Paul van Helden, Rob Warren, Keertan Dheda

The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates

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This paper is available in a repository.

2014 Janet P. Hapgood, Roslyn M. Ray, Yashini Govender, Chanel Avenant, Michele Tomasicchio

Differential Glucocorticoid Receptor-Mediated Effects on Immunomodulatory Gene Expression by Progestin Contraceptives: Implications for HIV-1 Pathogenesis

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All papers authored by Michele Tomasicchio