Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

van der Loeff, Ina Schim; Voysey, Merryn; Clemens, Sue Ann Costa; Madhi, Shabir A.; Weckx, Lily Y.; Green, Catherine M.; Folegatti, Pedro M.; Aley, Parvinder K.; Angus, Brian; Baillie, Vicky L.; Barnabas, Shaun L.; Bhorat, Qasim E.; Green, Christopher A.; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; Collins, Andrea M.; Colin-Jones, Rachel; Cutland, Clare L.; Darton, Thomas C.; Dheda, Keertan; Duncan, Christopher J. A.; Emary, Katherine R. W.; Sac, Clemens; Ewer, Katie J.; Fairlie, Lee; Faust, Saul N.; Feng, Shuo; Ferreira, Daniela M.; Finn, Adam; Goodman, Anna L.; O'Reilly, Paula J.; Heath, Paul T.; Hill, Catherine; Hill, Helen; Hirsch, Ian; Hodgson, Susanne H. C.; Izu, Alane; Jackson, Susan; Jenkin, Daniel; Joe, Carina C. D.; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; Sa, Madhi; Lawrie, Alison M.; Lelliott, Alice; Libri, Vincenzo; Lillie, Patrick J.; Mallory, Raburn; Mendes, Ana V. A.; Milan, Eveline P.; Minassian, Angela M.; McGregor, Alastair; Morrison, Hazel; Ly, Weckx; Mujadidi, Yama F.; Nana, Anusha; O’Reilly, Peter J.; Padayachee, Sherman D.; Pittella, Ana; Plested, Emma; Pm, Folegatti; Pollock, Katrina M.; Ramasamy, Maheshi N.; Rhead, Sarah; Schwarzbold, Alexandre V.; Singh, Nisha; Smith, Andrew; Song, Rinn; Snape, Matthew D.; Sprinz, Eduardo; Sutherland, Rebecca K.; Tarrant, Richard; Thomson, Emma C.; Török, M. Estée; Toshner, Mark; Turner, David P. J.; Pk, Aley; Vekemans, Johan; Villafana, Tonya L.; Watson, Marion E. E.; Williams, Christopher J.; Douglas, Alexander D.; Hill, Adrian V. S.; Lambe, Teresa; Gilbert, Sarah C.; Pollard, Andrew J.; Aban, Marites; Abayomi, Fatola; Abeyskera, Kushala; Aboagye, Jeremy; Adam, Matthew; Adams, Kirsty; Adamson, James; Vl, Baillie; Adelaja, Yemi A.; Adewetan, Gbadebo; Estée Török, M.; Adlou, Syed; Ahmed, Khatija; Akhalwaya, Yasmeen; Akhalwaya, Saajida; Alcock, Andrew; Ali, Aabidah; Allen, Elizabeth R.; Sl, Barnabas; Allen, Lauren; Almeida, Thamires C. D. S. C.; Alves, Mariana P. S.; Amorim, Fabio; Andritsou, Foteini; Anslow, Rachel; Appleby, Matthew; Arbe-Barnes, Edward H.; Ariaans, Mark P.; Arns, Beatriz; Arruda, Laiana; Azi, Paula; Azi, Lorena; Babbage, Gavin; Bailey, Catherine; Baker, Kenneth F.; Baker, Megan; Baker, Natalie; Baker, Philip; Baldwin, Lisa; Baleanu, Ioana; Bandeira, Danieli; Bara, Anna; Barbosa, Marcella A. S.; Barker, Debbie; Barlow, Gavin D.; Qe, Bhorat; Barnes, Eleanor; Barr, Andrew S.; Barrett, Jordan R.; Barrett, Jessica; Bates, Louise; Batten, Alexander; Beadon, Kirsten; Beales, Emily; Beckley, Rebecca; Belij-Rammerstorfer, Sandra; Bell, Jonathan; Bellamy, Duncan; Bellei, Nancy; Belton, Sue; Berg, Adam; Bermejo, Laura; Berrie, Eleanor; Berry, Lisa; Berzenyi, Daniella; Beveridge, Amy; Bewley, Kevin R.; Bexhell, Helen; Bhikha, Sutika; Bhorat, Asad E.; Bhorat, Zaheda E.; Bijker, Else; Birch, Geeta; Birch, Sarah; Bird, Adam; Bird, Olivia; Bisnauthsing, Karen; Bittaye, Mustapha; Blackstone, Katherine; Blackwell, Luke; Bletchly, Heather; Blundell, Caitlin L.; Blundell, Susannah R.; Bodalia, Pritesh; Boettger, Bruno C.; Bolam, Emma; Boland, Elena; Bormans, Daan; Borthwick, Nicola; Bowring, Francesca; Boyd, Amy; Bradley, Penny; Brenner, Tanja; Brown, Phillip; Brown, Claire; Brown-O'Sullivan, Charlie; Bruce, Scott; Brunt, Emily; Buchan, Ruaridh; Budd, William; Bulbulia, Yusuf A.; Bull, Melanie; Burbage, Jamie; Burhan, Hassan; Burn, Aileen; Buttigieg, Karen R.; Byard, Nicholas; Cabera Puig, Ingrid; Calderon, Gloria; Calvert, Anna; Puig, Ingrid Cabera; Camara, Susana; Cao, Michelangelo; Cappuccini, Federica; Cardoso, João R.; Carr, Melanie; Carroll, Miles W.; Carson-Stevens, Andrew; Carvalho, Yasmin de M.; Carvalho, José A. M.; Casey, Helen R.; Cashen, Paul; Castro, Thais; Castro, Lucia Carratala; Cathie, Katrina; Cavey, Ana; Cerbino-Neto, José; Chadwick, Jim; Chapman, David; Charlton, Sue; Chelysheva, Irina; Chester, Oliver; Chita, Sunder; Cho, Jee-Sun; Cifuentes, Liliana; Clark, Elizabeth; Clark, Matthew; Clarke, Andrea; Clutterbuck, Elizabeth A.; Collins, Sarah L. K.; Conlon, Christopher P.; Farias Da Guarda, Suzete N.; Connarty, Sean; Coombes, Naomi; Cooper, Cushla; Cooper, Rachel; Cornelissen, Lynne; Corrah, Tumena; Cosgrove, Catherine; Cox, Tony; Crocker, Wendy E. M.; Crosbie, Sarah; Cullen, Lorraine; Cullen, Dan; Cunha, Debora R. M. F.; Cunningham, Christina; Cuthbertson, Fiona C.; Da Guarda, Suzete N. Farias; da Silva, Larissa P.; Damratoski, Brad E.; Danos, Zsofia; Santos, Tannyth Dos; Dantas, Maria T. D. C.; Darroch, Paula; Datoo, Mehreen S.; Datta, Chandrabali; Santos, Erika Pachecho Dos; Davids, Malika; Davies, Sarah L.; Davies, Hannah; Davis, Elizabeth; Davis, Judith; Davis, John; De Nobrega, Maristela M. D.; De Oliveira Kalid, Lis Moreno; Dearlove, David; Demissie, Tesfaye; Desai, Amisha; Di Marco, Stefania; Di Maso, Claudio; Dinelli, Maria I. S.; Dinesh, Tanya; Docksey, Claire; Dold, Christina; Dong, Tao; Donnellan, Francesca R.; Dos Santos, Tannyth; dos Santos, Thainá G.; Dos Santos, Erika Pachecho; Da Silva, Carla Ferreira; Douglas, Naomi; Downing, Charlotte; Drake, Jonathan; Drake-Brockman, Rachael; Driver, Kimberley; Drury, Ruth; Dunachie, Susanna J.; Durham, Benjamin S.; Dutra, Lidiana; Easom, Nicholas J. W.; van Eck, Samual; Edwards, Mandy; Edwards, Nick J.; El Muhanna, Omar M.; Elias, Sean C.; Elmore, Mike; English, Marcus; Esmail, Alisgair; Essack, Yakub Moosa; Farmer, Eoghan; Farooq, Mutjaba; Farrar, Madi; Farrugia, Leonard; Faulkner, Beverley; Fedosyuk, Sofiya; Felle, Sally; Ferreira Da Silva, Carla; Field, Samantha; Fisher, Richard; Flaxman, Amy; Fletcher, James; Fofie, Hazel; Fok, Henry; Ford, Karen J.; Fowler, Jamie; Fraiman, Pedro H. A.; Francis, Emma; Franco, Marilia M.; Frater, John; Freire, Marilúcia S. M.; Fry, Samantha H.; Fudge, Sabrina; Furze, Julie; Fuskova, Michelle; Galian-Rubio, Pablo; Galiza, Eva; Garlant, Harriet; Gavrila, Madita; Geddes, Ailsa; Gibbons, Karyna A.; Gilbride, Ciaran; Gill, Hardeep; Glynn, Sharon; Godwin, Kerry; Gokani, Karishma; Goldoni, Ursula Carvalho; Goncalves, Maria; Gonzalez, Isabela G. S.; Goodwin, Jayne; Goondiwala, Amina; Gordon-Quayle, Katherine; Gorini, Giacomo; Grab, Janet; Gracie, Lara; Greenland, Melanie; Greenwood, Nicola; Greffrath, Johann; Groenewald, Marisa M.; Grossi, Leonardo; Gupta, Gaurav; Hackett, Mark; Hallis, Bassam; Hamaluba, Mainga; Hamilton, Elizabeth; Hamlyn, Joseph; Hammersley, Daniel; Hanrath, Aidan T.; Hanumunthadu, Brama; Harris, Stephanie A.; Harris, Clair; Harris, Tara; Harrison, Thomas D.; Harrison, Daisy; Hart, Thomas C.; Hartnell, Birgit; Hassan, Shadin; Haughney, John; Hawkins, Sophia; Hay, Jodie; Head, Ian; Henry, John; Hermosin Herrera, Macarena; Hettle, David B.; Hill, Jennifer; Hodges, Gina; Horne, Elizea; Hou, Mimi M.; Houlihan, Catherine; Howe, Elizabeth; Howell, Nicola; Hyder-Wright, Angela; Humphreys, Jonathan; Humphries, Holly E.; Ikram, Sabina; Hurley, Katrina; Ishwarbhai, Alka; Huson, Claire; Ivan, Monica; Iveson, Poppy; Hyams, Catherine; Iyer, Vidyashankara; Jackson, Frederic; Jaumdally, Shameem; Jeffers, Helen; De Jager, Jeanne; Jesudason, Natasha; Jones, Bryony; Jones, Kathryn; Jones, Elizabeth; Jones, Christopher; Jorge, Marianna Rocha; Jose, Aylin; Joshi, Amar; Júnior, Eduardo A. M. S.; Kadziola, Joanne; Kailath, Reshma; Kana, Faeeza; Karampatsas, Konstantinos; Kasanyinga, Mwila; Keen, Jade; Kelly, Elizabeth J.; Kelly, Dearbhla M.; Kelly, Debbie M.; Kelly, Sarah; Kerr, David; Kfouri, Renato de Ávila; Khan, Liaquat; Khozoee, Baktash; Kidd, Sarah; Killen, Annabel; Kinch, Jasmin; Kinch, Patrick; King, Lloyd D. W.; King, Thomas B.; Kingham, Lucy; Klenerman, Paul; Knapper, Francesca; Knight, Julian C.; Knott, Daniel; Koleva, Stanislava; Lang, Matilda; Lang, Gail; Larkworthy, Colin W.; Larwood, Jessica P. J.; Law, Rebecca; Lazarus, Erica M.; Leach, Amanda; Lees, Emily A.; Lemm, Nana-Marie; Lessa, Alvaro; Leung, Stephanie; Li, Yuanyuan; Lias, Amelia M.; Liatsikos, Kostas; Linder, Aline; Lipworth, Samuel; Liu, Shuchang; Liu, Xinxue; Lloyd, Adam; Lloyd, Stephanie; Loew, Lisa; Lopez Ramon, Raquel; Lora, Leandro; de Ávila Kfouri, Renato; Lowthorpe, Vicki; Luz, Kleber; MacDonald, Jonathan C.; MacGregor, Gordon; Madhavan, Meera; Mainwaring, David O.; Makambwa, Edson; Makinson, Rebecca; Malahleha, Mookho; Malamatsho, Ross; Mallett, Garry; Mansatta, Kushal; Maoko, Takalani; Mapetla, Katlego; Marchevsky, Natalie G.; Marinou, Spyridoula; Marlow, Emma; Marques, Gabriela N.; Marriott, Paula; Marshall, Richard P.; Marshall, Julia L.; Martins, Flávia J.; Masenya, Masebole; Masilela, Mduduzi; Masters, Shauna K.; Mathew, Moncy; Matlebjane, Hosea; Matshidiso, Kedidimetse; Mazur, Olga; Mazzella, Andrea; McCaughan, Hugh; McEwan, Joanne; McGlashan, Joanna; McInroy, Lorna; McIntyre, Zoe; McLenaghan, Daniela; McRobert, Nicky; Ramon, Raquel Lopez; McSwiggan, Steve; Megson, Clare; Mehdipour, Savviz; Meijs, Wilma; Mendonça, Renata N. Á.; Mentzer, Alexander J.; Mirtorabi, Neginsadat; Mitton, Celia; Mnyakeni, Sibusiso; Moghaddas, Fiona; Molapo, Kgaogelo; Moloi, Mapule; Moore, Maria; Moraes-Pinto, M. Isabel; Moran, Marni; Morey, Ella; Morgans, Róisín; Morris, Susan; Morris, Sheila; Morris, Helen C.; Morselli, Franca; Morshead, Gertraud; Morter, Richard; Mottal, Lynelle; Moultrie, Andrew; Moya, Nathifa; Mpelembue, Mushiya; Msomi, Sibekezelo; Mugodi, Yvonne; Mukhopadhyay, Ekta; Muller, Jilly; Munro, Alasdair; Munro, Claire; Murphy, Sarah; Mweu, Philomena; Myasaki, Celia Hatsuko; Naik, Gurudutt; Naker, Kush; Nastouli, Eleni; Nazir, Abida; Ndlovu, Bongani; Neffa, Fabio; Njenga, Cecilia; Noal, Helena; Noé, Andrés; Novaes, Gabrielle; Nugent, Fay L.; Isabel Moraes Pinto, M.; Nunes, Géssika; O'Brien, Katie; O'Connor, Daniel; Odam, Miranda; Oelofse, Suzette; Oguti, Blanche; Olchawski, Victoria; Oldfield, Neil J.; Oliveira, Marianne G.; Oliveira, Catarina; Oosthuizen, Angela; O'Reilly, Paula; Osborne, Piper; Owen, David R. J.; Owen, Lydia; Owens, Daniel; Owino, Nelly; Pacurar, Mihaela; Paiva, Brenda V. B.; Palhares, Edna M. F.; Palmer, Susan; O′Brien, Katie; Parkinson, Sivapriyai; Parracho, Helena M. R. T.; Parsons, Karen; Patel, Dipak; Patel, Bhumika; Patel, Faeezah; Patel, Kelly; O′Connor, Daniel; Patrick-Smith, Maia; Payne, Ruth O.; Peng, Yanchun; Penn, Elizabeth J.; Pennington, Anna; Peralta Alvarez, Marco Polo; O′Reilly, Paula; Perring, James; Perry, Nicola; Perumal, Rubeshan; Petkar, Sahir; Philip, Tricia; Phillips, Daniel J.; Phillips, Jennifer; Phohu, Mary Kgomotso; Pickup, Lorinda; Pieterse, Sonja; Piper, Jo; Pipini, Dimitra; Plank, Mary; Du Plessis, Joan; Pollard, Samuel; Pooley, Jennifer; Pooran, Anil; Poulton, Ian; Powers, Claire; Presa, Fernando B.; Price, David A.; Price, Vivien; Primeira, Marcelo; Proud, Pamela C.; Provstgaard-Morys, Samuel; Green, C. M.; Pueschel, Sophie; Pulido, David; Quaid, Sheena; Rabara, Ria; Radford, Alexandra; Green, C. A.; Radia, Kajal; Rajapaska, Durga; Rajeswaran, Thurkka; Ramos, Alberto San Francisco; Ramos Lopez, Fernando; Rampling, Tommy; Rand, Jade; Ratcliffe, Helen; Rawlinson, Tom; Rea, David; Rees, Byron; Reiné, Jesús; Resuello-Dauti, Mila; Reyes Pabon, Emilia; Pabon, Emilia Reyes; Ribiero, Carla M.; Ricamara, Marivic; Richter, Alex; Ritchie, Neil; Ritchie, Adam J.; Robbins, Alexander J.; Roberts, Hannah; Robinson, Ryan E.; Robinson, Hannah; Rocchetti, Talita T.; Rocha, Beatriz Pinho; Roche, Sophie; Rollier, Christine; Rose, Louisa; Ross Russell, Amy L.; Rossouw, Lindie; Royal, Simon; Rudiansyah, Indra; Ruiz, Sarah; Saich, Stephen; Sala, Claudia; Sale, Jessica; Salman, Ahmed M.; Salvador, Natalia; Salvador, Stephannie; Sampaio, Milla; Samson, Annette D.; Sanchez-Gonzalez, Amada; Sanders, Helen; Sanders, Katherine; Santos, Erika; Santos Guerra, Mayara F. S.; Satti, Iman; Saunders, Jack E.; Saunders, Caroline; Sayed, Aakifah; Schim van der Loeff, Ina; Schmid, Annina B.; Schofield, Ella; Screaton, Gavin; Seddiqi, Samiullah; Segireddy, Rameswara R.; Senger, Roberta; Serrano, Sonia; Shah, Rajiv; Shaik, Imam; Sharpe, Hannah E.; Alvarez, Marco Polo Peralta; Sharrocks, Katherine; Shaw, Robert; Shea, Adam; Shepherd, Amy; Shepherd, James G.; Shiham, Farah; Sidhom, Emad; Silk, Sarah E.; da Silva Moraes, Antonio Carlos; Silva-Junior, Gilberto; Silva-Reyes, Laura; Silveira, Anderson D.; Silveira, Mariana B. V.; Sinha, Jaisi; Skelly, Donal T.; Smith, Daniel C.; Smith, Nick; Smith, Holly E.; Smith, David J.; Smith, Catherine C.; Soares, Airanuédida; Soares, Tiago; Solórzano, Carla; Sorio, Guilherme L.; Sorley, Kim; Sosa-Rodriguez, Tiffany; Souza, Cinthia M. C. D. L.; Souza, Bruno S. D. F.; Souza, Alessandra R.; Spencer, Alexandra J.; Spina, Fernanda; Spoors, Louise; Stafford, Lizzie; Stamford, Imogen; Starinskij, Igor; Stein, Ricardo; Steven, Jill; Stockdale, Lisa; Stockwell, Lisa V.; Awedetan, Gbadebo; Strickland, Louise H.; Stuart, Arabella C.; Sturdy, Ann; Sutton, Natalina; Szigeti, Anna; Tahiri-Alaoui, Abdessamad; Tanner, Rachel; Taoushanis, Carol; Tarr, Alexander W.; Taylor, Keja; Naude, Rebecca te Water; Taylor, Ursula; Taylor, Iona Jennifer; Taylor, Justin; te Water Naude, Rebecca; Themistocleous, Yrene; Themistocleous, Andreas; Thomas, Merin; Thomas, Kelly; Thomas, Tonia M.; Thombrayil, Asha; Thompson, Fawziyah; Thompson, Amber; Thompson, Kevin; Thompson, Ameeka; Thomson, Julia; Thornton-Jones, Viv; Tighe, Patrick J.; Tinoco, Lygia Accioly; Tiongson, Gerlynn; Tladinyane, Bonolo; Tomasicchio, Michele; Tomic, Adriana; Tonks, Susan; Towner, James; Tran, Nguyen; Tree, Julia; Trillana, Gerry; Trinham, Charlotte; Trivett, Rose; Truby, Adam; Tsheko, Betty Lebogang; Turabi, Aadil; Turner, Richard; Turner, Cheryl; Ulaszewska, Marta; Underwood, Benjamin R.; Varughese, Rachel; Verbart, Dennis; Verheul, Marije; Vichos, Iason; Waddington, Claire S.; Vieira, Taiane; Walker, Laura; Wallis, Erica; Wand, Matthew; Warbick, Deborah; Wardell, Theresa; Warimwe, George; Warren, Sarah C.; Watkins, Bridget; Watson, Ekaterina; Webb, Stewart; Webb-Bridges, Alice; Webster, Angela; Welch, Jessica; Wells, Jeanette; West, Alison; White, Caroline; White, Rachel; Williams, Paul; Williams, Rachel L.; Winslow, Rebecca; Woodyer, Mark; Worth, Andrew T.; Wright, Danny; Wroblewska, Marzena; Yao, Andy; Zimmer, Rafael; Zizi, Dalila; Hyamns, Catherine; Zuidewind, Peter; Group, Oxford Covid Vaccine Trial

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Pedro Folegatti
van der Loeff et al., 2020

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Elsevier, The Lancet, 10269(397), p. 99-111, 2021

DOI: 10.1016/s0140-6736(20)32661-1

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@article{van der Loeff2020,
  author = {van der Loeff, Ina Schim and Voysey, Merryn and Clemens, Sue Ann Costa and Madhi, Shabir A. and Weckx, Lily Y. and Green, Catherine M. and Folegatti, Pedro M. and Aley, Parvinder K. and Angus, Brian and Baillie, Vicky L. and Barnabas, Shaun L. and Bhorat, Qasim E. and Green, Christopher A. and Bibi, Sagida and Briner, Carmen and Cicconi, Paola and Collins, Andrea M. and Colin-Jones, Rachel and Cutland, Clare L. and Darton, Thomas C. and Dheda, Keertan and Duncan, Christopher J. A. and Emary, Katherine R. W. and Sac, Clemens and Ewer, Katie J. and Fairlie, Lee and Faust, Saul N. and Feng, Shuo and Ferreira, Daniela M. and Finn, Adam and Goodman, Anna L. and O'Reilly, Paula J. and Heath, Paul T. and Hill, Catherine and Hill, Helen and Hirsch, Ian and Hodgson, Susanne H. C. and Izu, Alane and Jackson, Susan and Jenkin, Daniel and Joe, Carina C. D. and Kerridge, Simon and Koen, Anthonet and Kwatra, Gaurav and Lazarus, Rajeka and Sa, Madhi and Lawrie, Alison M. and Lelliott, Alice and Libri, Vincenzo and Lillie, Patrick J. and Mallory, Raburn and Mendes, Ana V. A. and Milan, Eveline P. and Minassian, Angela M. and McGregor, Alastair and Morrison, Hazel and Ly, Weckx and Mujadidi, Yama F. and Nana, Anusha and O’Reilly, Peter J. and Padayachee, Sherman D. and Pittella, Ana and Plested, Emma and Pm, Folegatti and Pollock, Katrina M. and Ramasamy, Maheshi N. and Rhead, Sarah and Schwarzbold, Alexandre V. and Singh, Nisha and Smith, Andrew and Song, Rinn and Snape, Matthew D. and Sprinz, Eduardo and Sutherland, Rebecca K. and Tarrant, Richard and Thomson, Emma C. and Török, M. Estée and Toshner, Mark and Turner, David P. J. and Pk, Aley and Vekemans, Johan and Villafana, Tonya L. and Watson, Marion E. E. and Williams, Christopher J. and Douglas, Alexander D. and Hill, Adrian V. S. and Lambe, Teresa and Gilbert, Sarah C. and Pollard, Andrew J. and Aban, Marites and Abayomi, Fatola and Abeyskera, Kushala and Aboagye, Jeremy and Adam, Matthew and Adams, Kirsty and Adamson, James and Vl, Baillie and Adelaja, Yemi A. and Adewetan, Gbadebo and Estée Török, M. and Adlou, Syed and Ahmed, Khatija and Akhalwaya, Yasmeen and Akhalwaya, Saajida and Alcock, Andrew and Ali, Aabidah and Allen, Elizabeth R. and Sl, Barnabas and Allen, Lauren and Almeida, Thamires C. D. S. C. and Alves, Mariana P. S. and Amorim, Fabio and Andritsou, Foteini and Anslow, Rachel and Appleby, Matthew and Arbe-Barnes, Edward H. and Ariaans, Mark P. and Arns, Beatriz and Arruda, Laiana and Azi, Paula and Azi, Lorena and Babbage, Gavin and Bailey, Catherine and Baker, Kenneth F. and Baker, Megan and Baker, Natalie and Baker, Philip and Baldwin, Lisa and Baleanu, Ioana and Bandeira, Danieli and Bara, Anna and Barbosa, Marcella A. S. and Barker, Debbie and Barlow, Gavin D. and Qe, Bhorat and Barnes, Eleanor and Barr, Andrew S. and Barrett, Jordan R. and Barrett, Jessica and Bates, Louise and Batten, Alexander and Beadon, Kirsten and Beales, Emily and Beckley, Rebecca and Belij-Rammerstorfer, Sandra and Bell, Jonathan and Bellamy, Duncan and Bellei, Nancy and Belton, Sue and Berg, Adam and Bermejo, Laura and Berrie, Eleanor and Berry, Lisa and Berzenyi, Daniella and Beveridge, Amy and Bewley, Kevin R. and Bexhell, Helen and Bhikha, Sutika and Bhorat, Asad E. and Bhorat, Zaheda E. and Bijker, Else and Birch, Geeta and Birch, Sarah and Bird, Adam and Bird, Olivia and Bisnauthsing, Karen and Bittaye, Mustapha and Blackstone, Katherine and Blackwell, Luke and Bletchly, Heather and Blundell, Caitlin L. and Blundell, Susannah R. and Bodalia, Pritesh and Boettger, Bruno C. and Bolam, Emma and Boland, Elena and Bormans, Daan and Borthwick, Nicola and Bowring, Francesca and Boyd, Amy and Bradley, Penny and Brenner, Tanja and Brown, Phillip and Brown, Claire and Brown-O'Sullivan, Charlie and Bruce, Scott and Brunt, Emily and Buchan, Ruaridh and Budd, William and Bulbulia, Yusuf A. and Bull, Melanie and Burbage, Jamie and Burhan, Hassan and Burn, Aileen and Buttigieg, Karen R. and Byard, Nicholas and Cabera Puig, Ingrid and Calderon, Gloria and Calvert, Anna and Puig, Ingrid Cabera and Camara, Susana and Cao, Michelangelo and Cappuccini, Federica and Cardoso, João R. and Carr, Melanie and Carroll, Miles W. and Carson-Stevens, Andrew and Carvalho, Yasmin de M. and Carvalho, José A. M. and Casey, Helen R. and Cashen, Paul and Castro, Thais and Castro, Lucia Carratala and Cathie, Katrina and Cavey, Ana and Cerbino-Neto, José and Chadwick, Jim and Chapman, David and Charlton, Sue and Chelysheva, Irina and Chester, Oliver and Chita, Sunder and Cho, Jee-Sun and Cifuentes, Liliana and Clark, Elizabeth and Clark, Matthew and Clarke, Andrea and Clutterbuck, Elizabeth A. and Collins, Sarah L. K. and Conlon, Christopher P. and Farias Da Guarda, Suzete N. and Connarty, Sean and Coombes, Naomi and Cooper, Cushla and Cooper, Rachel and Cornelissen, Lynne and Corrah, Tumena and Cosgrove, Catherine and Cox, Tony and Crocker, Wendy E. M. and Crosbie, Sarah and Cullen, Lorraine and Cullen, Dan and Cunha, Debora R. M. F. and Cunningham, Christina and Cuthbertson, Fiona C. and Da Guarda, Suzete N. Farias and da Silva, Larissa P. and Damratoski, Brad E. and Danos, Zsofia and Santos, Tannyth Dos and Dantas, Maria T. D. C. and Darroch, Paula and Datoo, Mehreen S. and Datta, Chandrabali and Santos, Erika Pachecho Dos and Davids, Malika and Davies, Sarah L. and Davies, Hannah and Davis, Elizabeth and Davis, Judith and Davis, John and De Nobrega, Maristela M. D. and De Oliveira Kalid, Lis Moreno and Dearlove, David and Demissie, Tesfaye and Desai, Amisha and Di Marco, Stefania and Di Maso, Claudio and Dinelli, Maria I. S. and Dinesh, Tanya and Docksey, Claire and Dold, Christina and Dong, Tao and Donnellan, Francesca R. and Dos Santos, Tannyth and dos Santos, Thainá G. and Dos Santos, Erika Pachecho and Da Silva, Carla Ferreira and Douglas, Naomi and Downing, Charlotte and Drake, Jonathan and Drake-Brockman, Rachael and Driver, Kimberley and Drury, Ruth and Dunachie, Susanna J. and Durham, Benjamin S. and Dutra, Lidiana and Easom, Nicholas J. W. and van Eck, Samual and Edwards, Mandy and Edwards, Nick J. and El Muhanna, Omar M. and Elias, Sean C. and Elmore, Mike and English, Marcus and Esmail, Alisgair and Essack, Yakub Moosa and Farmer, Eoghan and Farooq, Mutjaba and Farrar, Madi and Farrugia, Leonard and Faulkner, Beverley and Fedosyuk, Sofiya and Felle, Sally and Ferreira Da Silva, Carla and Field, Samantha and Fisher, Richard and Flaxman, Amy and Fletcher, James and Fofie, Hazel and Fok, Henry and Ford, Karen J. and Fowler, Jamie and Fraiman, Pedro H. A. and Francis, Emma and Franco, Marilia M. and Frater, John and Freire, Marilúcia S. M. and Fry, Samantha H. and Fudge, Sabrina and Furze, Julie and Fuskova, Michelle and Galian-Rubio, Pablo and Galiza, Eva and Garlant, Harriet and Gavrila, Madita and Geddes, Ailsa and Gibbons, Karyna A. and Gilbride, Ciaran and Gill, Hardeep and Glynn, Sharon and Godwin, Kerry and Gokani, Karishma and Goldoni, Ursula Carvalho and Goncalves, Maria and Gonzalez, Isabela G. S. and Goodwin, Jayne and Goondiwala, Amina and Gordon-Quayle, Katherine and Gorini, Giacomo and Grab, Janet and Gracie, Lara and Greenland, Melanie and Greenwood, Nicola and Greffrath, Johann and Groenewald, Marisa M. and Grossi, Leonardo and Gupta, Gaurav and Hackett, Mark and Hallis, Bassam and Hamaluba, Mainga and Hamilton, Elizabeth and Hamlyn, Joseph and Hammersley, Daniel and Hanrath, Aidan T. and Hanumunthadu, Brama and Harris, Stephanie A. and Harris, Clair and Harris, Tara and Harrison, Thomas D. and Harrison, Daisy and Hart, Thomas C. and Hartnell, Birgit and Hassan, Shadin and Haughney, John and Hawkins, Sophia and Hay, Jodie and Head, Ian and Henry, John and Hermosin Herrera, Macarena and Hettle, David B. and Hill, Jennifer and Hodges, Gina and Horne, Elizea and Hou, Mimi M. and Houlihan, Catherine and Howe, Elizabeth and Howell, Nicola and Hyder-Wright, Angela and Humphreys, Jonathan and Humphries, Holly E. and Ikram, Sabina and Hurley, Katrina and Ishwarbhai, Alka and Huson, Claire and Ivan, Monica and Iveson, Poppy and Hyams, Catherine and Iyer, Vidyashankara and Jackson, Frederic and Jaumdally, Shameem and Jeffers, Helen and De Jager, Jeanne and Jesudason, Natasha and Jones, Bryony and Jones, Kathryn and Jones, Elizabeth and Jones, Christopher and Jorge, Marianna Rocha and Jose, Aylin and Joshi, Amar and Júnior, Eduardo A. M. S. and Kadziola, Joanne and Kailath, Reshma and Kana, Faeeza and Karampatsas, Konstantinos and Kasanyinga, Mwila and Keen, Jade and Kelly, Elizabeth J. and Kelly, Dearbhla M. and Kelly, Debbie M. and Kelly, Sarah and Kerr, David and Kfouri, Renato de Ávila and Khan, Liaquat and Khozoee, Baktash and Kidd, Sarah and Killen, Annabel and Kinch, Jasmin and Kinch, Patrick and King, Lloyd D. W. and King, Thomas B. and Kingham, Lucy and Klenerman, Paul and Knapper, Francesca and Knight, Julian C. and Knott, Daniel and Koleva, Stanislava and Lang, Matilda and Lang, Gail and Larkworthy, Colin W. and Larwood, Jessica P. J. and Law, Rebecca and Lazarus, Erica M. and Leach, Amanda and Lees, Emily A. and Lemm, Nana-Marie and Lessa, Alvaro and Leung, Stephanie and Li, Yuanyuan and Lias, Amelia M. and Liatsikos, Kostas and Linder, Aline and Lipworth, Samuel and Liu, Shuchang and Liu, Xinxue and Lloyd, Adam and Lloyd, Stephanie and Loew, Lisa and Lopez Ramon, Raquel and Lora, Leandro and de Ávila Kfouri, Renato and Lowthorpe, Vicki and Luz, Kleber and MacDonald, Jonathan C. and MacGregor, Gordon and Madhavan, Meera and Mainwaring, David O. and Makambwa, Edson and Makinson, Rebecca and Malahleha, Mookho and Malamatsho, Ross and Mallett, Garry and Mansatta, Kushal and Maoko, Takalani and Mapetla, Katlego and Marchevsky, Natalie G. and Marinou, Spyridoula and Marlow, Emma and Marques, Gabriela N. and Marriott, Paula and Marshall, Richard P. and Marshall, Julia L. and Martins, Flávia J. and Masenya, Masebole and Masilela, Mduduzi and Masters, Shauna K. and Mathew, Moncy and Matlebjane, Hosea and Matshidiso, Kedidimetse and Mazur, Olga and Mazzella, Andrea and McCaughan, Hugh and McEwan, Joanne and McGlashan, Joanna and McInroy, Lorna and McIntyre, Zoe and McLenaghan, Daniela and McRobert, Nicky and Ramon, Raquel Lopez and McSwiggan, Steve and Megson, Clare and Mehdipour, Savviz and Meijs, Wilma and Mendonça, Renata N. 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A. and Radia, Kajal and Rajapaska, Durga and Rajeswaran, Thurkka and Ramos, Alberto San Francisco and Ramos Lopez, Fernando and Rampling, Tommy and Rand, Jade and Ratcliffe, Helen and Rawlinson, Tom and Rea, David and Rees, Byron and Reiné, Jesús and Resuello-Dauti, Mila and Reyes Pabon, Emilia and Pabon, Emilia Reyes and Ribiero, Carla M. and Ricamara, Marivic and Richter, Alex and Ritchie, Neil and Ritchie, Adam J. and Robbins, Alexander J. and Roberts, Hannah and Robinson, Ryan E. and Robinson, Hannah and Rocchetti, Talita T. and Rocha, Beatriz Pinho and Roche, Sophie and Rollier, Christine and Rose, Louisa and Ross Russell, Amy L. and Rossouw, Lindie and Royal, Simon and Rudiansyah, Indra and Ruiz, Sarah and Saich, Stephen and Sala, Claudia and Sale, Jessica and Salman, Ahmed M. and Salvador, Natalia and Salvador, Stephannie and Sampaio, Milla and Samson, Annette D. and Sanchez-Gonzalez, Amada and Sanders, Helen and Sanders, Katherine and Santos, Erika and Santos Guerra, Mayara F. S. and Satti, Iman and Saunders, Jack E. and Saunders, Caroline and Sayed, Aakifah and Schim van der Loeff, Ina and Schmid, Annina B. and Schofield, Ella and Screaton, Gavin and Seddiqi, Samiullah and Segireddy, Rameswara R. and Senger, Roberta and Serrano, Sonia and Shah, Rajiv and Shaik, Imam and Sharpe, Hannah E. and Alvarez, Marco Polo Peralta and Sharrocks, Katherine and Shaw, Robert and Shea, Adam and Shepherd, Amy and Shepherd, James G. and Shiham, Farah and Sidhom, Emad and Silk, Sarah E. and da Silva Moraes, Antonio Carlos and Silva-Junior, Gilberto and Silva-Reyes, Laura and Silveira, Anderson D. and Silveira, Mariana B. V. and Sinha, Jaisi and Skelly, Donal T. and Smith, Daniel C. and Smith, Nick and Smith, Holly E. and Smith, David J. and Smith, Catherine C. and Soares, Airanuédida and Soares, Tiago and Solórzano, Carla and Sorio, Guilherme L. and Sorley, Kim and Sosa-Rodriguez, Tiffany and Souza, Cinthia M. C. D. L. and Souza, Bruno S. D. F. and Souza, Alessandra R. and Spencer, Alexandra J. and Spina, Fernanda and Spoors, Louise and Stafford, Lizzie and Stamford, Imogen and Starinskij, Igor and Stein, Ricardo and Steven, Jill and Stockdale, Lisa and Stockwell, Lisa V. and Awedetan, Gbadebo and Strickland, Louise H. and Stuart, Arabella C. and Sturdy, Ann and Sutton, Natalina and Szigeti, Anna and Tahiri-Alaoui, Abdessamad and Tanner, Rachel and Taoushanis, Carol and Tarr, Alexander W. and Taylor, Keja and Naude, Rebecca te Water and Taylor, Ursula and Taylor, Iona Jennifer and Taylor, Justin and te Water Naude, Rebecca and Themistocleous, Yrene and Themistocleous, Andreas and Thomas, Merin and Thomas, Kelly and Thomas, Tonia M. and Thombrayil, Asha and Thompson, Fawziyah and Thompson, Amber and Thompson, Kevin and Thompson, Ameeka and Thomson, Julia and Thornton-Jones, Viv and Tighe, Patrick J. and Tinoco, Lygia Accioly and Tiongson, Gerlynn and Tladinyane, Bonolo and Tomasicchio, Michele and Tomic, Adriana and Tonks, Susan and Towner, James and Tran, Nguyen and Tree, Julia and Trillana, Gerry and Trinham, Charlotte and Trivett, Rose and Truby, Adam and Tsheko, Betty Lebogang and Turabi, Aadil and Turner, Richard and Turner, Cheryl and Ulaszewska, Marta and Underwood, Benjamin R. and Varughese, Rachel and Verbart, Dennis and Verheul, Marije and Vichos, Iason and Waddington, Claire S. and Vieira, Taiane and Walker, Laura and Wallis, Erica and Wand, Matthew and Warbick, Deborah and Wardell, Theresa and Warimwe, George and Warren, Sarah C. and Watkins, Bridget and Watson, Ekaterina and Webb, Stewart and Webb-Bridges, Alice and Webster, Angela and Welch, Jessica and Wells, Jeanette and West, Alison and White, Caroline and White, Rachel and Williams, Paul and Williams, Rachel L. and Winslow, Rebecca and Woodyer, Mark and Worth, Andrew T. and Wright, Danny and Wroblewska, Marzena and Yao, Andy and Zimmer, Rafael and Zizi, Dalila and Hyamns, Catherine and Zuidewind, Peter and Group, Oxford Covid Vaccine Trial},
  doi = {10.1016/s0140-6736(20)32661-1},
  journal = {The Lancet},
  month = {dec},
  pages = {99-111},
  title = {Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK},
  url = {https://oadoi.org/10.1016/s0140-6736(20)32661-1},
  volume = {397},
  year = {2020}
}

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