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Royal Society of Chemistry, Chemical Communications, 47(56), p. 6392-6395, 2020

DOI: 10.1039/d0cc02429e

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Triazole-based, optically-pure metallosupramolecules; highly potent and selective anticancer compounds

Journal article published in 2020 by Hualong Song ORCID, Nicola J. Rogers ORCID, Viktor Brabec ORCID, Guy J. Clarkson ORCID, James P. C. Coverdale ORCID, Hana Kostrhunova ORCID, Roger M. Phillips ORCID, Miles Postings ORCID, Samantha L. Shepherd ORCID, Peter Scott ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Click-derived functionalised triazoles self-assemble to water-compatible, optically pure, low symmetry metallohelices that display sub-micromolar antiproliferative activity, excellent selectivity and synergistic combination with cisplatin.