Viktor Brabec - Dissemin

All papers authored by Viktor Brabec

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Jitka Prachařová

, Hana Kostrhunová

, Alessandra Barbanente

, Nicola Margiotta

, Viktor Brabec

The mechanism of antiproliferative activity of the oxaliplatin pyrophosphate derivative involves its binding to nuclear DNA in cancer cells

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Vojtech Novohradsky

, Alicia Marco

, Lenka Markova

, Natalia Cutillas, José Ruiz

, Viktor Brabec

Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells

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Jaroslav Malina, Hana Kostrhunova

, Peter Scott, Viktor Brabec

Metallohelices stabilize DNA three-way junctions and induce DNA damage in cancer cells

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Hana Kostrhunova

, Brondwyn S. McGhie, Lenka Markova

, Olga Novakova, Jana Kasparkova

, Janice R. Aldrich-Wright

, Viktor Brabec

Platinum(IV) Derivatives of [Pt(1S,2S-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells

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Alba Hernández-García, Lenka Marková

, María Dolores Santana

, Jitka Prachařová, Delia Bautista, Hana Kostrhunová, Vojtěch Novohradský

, Viktor Brabec

, José Ruiz

, Jana Kašpárková

Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis

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J. P. C. Coverdale

, H. Kostrhunova

, L. Markova

, H. Song

, M. Postings

, H. E. Bridgewater

, V. Brabec

, N. J. Rogers

, P. Scott

Triplex metallohelices have enantiomer-dependent mechanisms of action in colon cancer cells

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2022 Jakub Cervinka, Alberto Gobbo, Lorenzo Biancalana

, Lenka Markova

, Vojtech Novohradsky

, Massimo Guelfi, Stefano Zacchini

, Jana Kasparkova

, Viktor Brabec

, Fabio Marchetti

Ruthenium(II)–Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis

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Monika Hreusova

, Enrico Rizzarelli, Vojtech Novohradsky

, Lenka Markova

, Hana Kostrhunova

, Ivan Potočňák

, Viktor Brabec

, Jana Kasparkova

Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells

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Jaroslav Malina

, Hana Kostrhunova, Vojtech Novohradsky, Peter Scott, Viktor Brabec

Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles

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Vojtech Novohradsky

, Lenka Markova

, Hana Kostrhunova

, Marie Svitelova, Jana Kasparkova

, Alessandra Barbanente, Paride Papadia

, Nicola Margiotta

, James D. Hoeschele, Viktor Brabec

Pt(ii) complex containing the 1R,2R enantiomer of trans-1,2-diamino-4-cyclohexene ligand effectively and selectively inhibits the viability of aggressive pancreatic adenocarcinoma cells and alters their lipid metabolism

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Jaroslav Malina

, Hana Kostrhunova

, Viktor Brabec

Dinuclear nickel(ii) supramolecular helicates down-regulate gene expression in human cells by stabilizing DNA G-quadruplexes formed in the promoter regions

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2021 Claudia Schmidt, Tomer Babu

, Hana Kostrhunova, Annika Timm, Uttara Basu, Ingo Ott, Valentina Gandin, Viktor Brabec

, Dan Gibson

Are Pt(IV) Prodrugs That Release Combretastatin A4 True Multi-action Prodrugs?

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Jaroslav Malina

, Hana Kostrhunova, Peter Scott, Viktor Brabec

Fe^II Metallohelices Stabilize DNA G‐Quadruplexes and Downregulate the Expression of G‐Quadruplex‐Regulated Oncogenes

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Huayun Shi

, Jana Kasparkova

, Clément Soulié

, Guy J. Clarkson

, Cinzia Imberti

, Olga Novakova

, Martin J. Paterson

, Viktor Brabec

, Peter J. Sadler

DNA‐Intercalative Platinum Anticancer Complexes Photoactivated by Visible Light

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Vojtech Novohradsky

, Lenka Markova

, Hana Kostrhunova

, Jana Kasparkova

, José Ruiz

, Vicente Marchán

, Viktor Brabec

A Cyclometalated Ir^III Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells

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Gloria Vigueras

, Lenka Markova

, Vojtech Novohradsky

, Alicia Marco

, Natalia Cutillas

, Hana Kostrhunova

, Jana Kasparkova

, José Ruiz

, Viktor Brabec

A photoactivated Ir(iii) complex targets cancer stem cells and induces secretion of damage-associated molecular patterns in melanoma cells characteristic of immunogenic cell death

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Jaroslav Malina

, Hana Kostrhunova, Nicholas P. Farrell

, Viktor Brabec

Antitumor substitution-inert polynuclear platinum complexes stabilize G-quadruplex DNA and suppress G-quadruplex-mediated gene expression

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Lukáš Masaryk, Ivan Nemec

, Jana Kašpárková

, Viktor Brabec

, Pavel Štarha

Unexpected solution behaviour of ester-functionalized half-sandwich Ru(ii) and Ir(iii) complexes

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2020 Subhendu Karmakar

, Hana Kostrhunova, Tereza Ctvrtlikova, Vojtech Novohradsky

, Dan Gibson

, Viktor Brabec

Platinum(IV)-Estramustine Multiaction Prodrugs Are Effective Antiproliferative Agents against Prostate Cancer Cells

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All papers authored by Viktor Brabec