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All papers authored by Michael Beer

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2024 Nichole K. Stewart, Marta Toth, Pojun Quan, Michael Beer

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, John D. Buynak

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, Clyde A. Smith

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, Sergei B. Vakulenko

ORCID

Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase

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2023 Catherine L. Tooke

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, Philip Hinchliffe

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, Michael Beer

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, Kirill Zinovjev

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, Charlotte K. Colenso, Christopher J. Schofield

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, Adrian J. Mulholland

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, James Spencer

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Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase

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2022 Catherine Tooke, Philip Hinchliffe, Michael Beer

ORCID

, Kirill Zinovjev, Charlotte K. Colenso, Christopher J. Schofield, Adrian Mulholland, James Spencer

Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase

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Ewa I. Chudyk, Michael Beer

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, Michael A. L. Limb, Charlotte A. Jones, James Spencer

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, Marc W. van der Kamp

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, Adrian J. Mulholland

ORCID

QM/MM Simulations Reveal the Determinants of Carbapenemase Activity in Class A β-Lactamases

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