Ludovic Jean - Dissemin

All papers authored by Ludovic Jean

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2023 Aurélie Gernet, Ahmed El Rhaz, Ludovic Jean

Easily Accessible Substituted Heterocyclic Hemithioindigos as Bistable Molecular Photoswitches

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Steve Saulnier, Nawel Mehiaoui, Stéphane Leleu, Ludovic Jean

Accessing 7‐Azaaurones of Controllable E and Z Configurations from 8‐Azaflavones via a Rearrangement‐Acylation‐Photoisomerization Sequence

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2022 Ophélie Da Silva, Nicolas Probst, Christophe Landry, Anne-Sophie Hanak, Pierre Warnault, Caroline Coisne, André-Guilhem Calas, Fabien Gosselet

, Charlotte Courageux, Anne-Julie Gastellier, Marilène Trancart, Rachid Baati, Marie-Pierre Dehouck, Ludovic Jean

, Florian Nachon

and 2 other authors

A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning

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2021 Antonin Delaune, Sergui Mansour, Baptiste Picard, Philippe Carrasqueira, Isabelle Chataigner

, Ludovic Jean

, Pierre-Yves Renard

, Jean-Christophe M. Monbaliu

, Julien Legros

Flow neutralisation of sulfur-containing chemical warfare agents with Oxone: packed bed vs. aqueous solution

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2020 Elisabet Viayna, Nicolas Coquelle, Monika Cieslikiewicz-Bouet, Pedro Cisternas, Carolina A. Oliva, Elena Sánchez-López, Miren Ettcheto

, Manuela Bartolini

, Angela De Simone, Mattia Ricchini, Marisa Rendina, Mégane Pons, Omidreza Firuzi, Belén Pérez, Luciano Saso and 11 other authors

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

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Monika Cieslikiewicz-Bouet, Marina Naldi, Manuela Bartolini, Belén Pérez, Denis Servent, Ludovic Jean

, Rómulo Aráoz, Pierre-Yves Renard

Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor

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Tamara Zorbaz, Petra Mišetić, Nicolas Probst, Suzana Žunec, Antonio Zandona, Gordana Mendaš, Vedran Micek, Nikolina Maček Hrvat, Maja Katalinić, Anissa Braïki, Ludovic Jean

, Pierre-Yves Renard

, Vesna Gabelica Marković, Zrinka Kovarik

Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning

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This paper is made freely available by the publisher.

2019 Mégane Pons, Ludovic Jean

, Sylvain Routier, Frédéric Buron, Sylvie Chalon, Pierre-Yves Renard

Toward an Innovative Treatment of Alzheimer’s Disease: Design of MTDLs Targeting Acetylcholinesterase and α-7 Nicotinic Receptors

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Pierrick Bruyat, Ludovic Jean

, Pierre-Yves Renard

Regioselective Solid-Phase Synthesis of Peptide Analogues Containing 3,4- or 3,5-Disubstituted Isoxazole as s-cis or s-trans Peptide Bond Mimics

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Killian Oukoloff, Nicolas Coquelle, Manuela Bartolini, Marina Naldi, Rémy Le Guevel, Stéphane Bach, Béatrice Josselin, Sandrine Ruchaud, Marco Catto, Leonardo Pisani, Nunzio Denora, Rosa Maria Iacobazzi, Israel Silman, Joel L. Sussman, Frédéric Buron and 4 other authors

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3

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2018 Tatiana N. Pashirova, Anissa Braïki, Irina V. Zueva, Konstantin A. Petrov, Vasily M. Babaev, Evgenia A. Burilova, Darya A. Samarkina, Ildar K.-H. Rizvanov, Eliana B. Souto

, Ludovic Jean

, Pierre-Yves Renard, Patrick Masson, Lucia Y.-A. Zakharova, Oleg G. Sinyashin

Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection

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Pierrick Bruyat, Arnaud Gautier, Ludovic Jean

, Pierre-Yves Renard

Use of an Air-Stable Cu(I)-NHC Catalyst for the Synthesis of Peptidotriazoles

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Gianluca Santoni

, Julien de Sousa, Eugenio de la Mora, José Dias

, Ludovic Jean

, Joel L. Sussman, Israel Silman, Pierre-Yves Renard, Richard C. D. Brown, Martin Weik, Rachid Baati, Florian Nachon

Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

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Tamara Zorbaz

, Anissa Braïki, Nikola Maraković, Julien Renou, Eugenio de la Mora, Nikolina Maček Hrvat

, Maja Katalinić

, Israel Silman, Joel L. Sussman, Guillaume Mercey, Catherine Gomez, Romain Mougeot, Belén Pérez

, Rachid Baati

, Florian Nachon

and 4 other authors

Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration

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Carles Galdeano, Nicolas Coquelle, Monika Cieslikiewicz-Bouet, Manuela Bartolini, Belén Pérez, M. Clos, Israel Silman, Ludovic Jean

, Jacques-Philippe Colletier, Pierre-Yves Renard, Diego Muñoz-Torrero

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis

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2017 Paul Hermant, Damien Bosc, Catherine Piveteau, Ronan Gealageas, BaoVy Lam, Cyril Ronco, Matthieu Roignant, Hasina Tolojanahary, Ludovic Jean

, Pierre-Yves Renard, Mohamed Lemdani, Marilyne Bourotte, Adrien Herledan, Corentin Bedart, Alexandre Biela and 3 other authors

Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox

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Pierre-Yves Renard, Ludovic Jean

Probing the cholinergic system to understand neurodegenerative diseases

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2016 André-Guilhem Calas, José Dias

, Catherine Rousseau, Mélanie Arboléas, Mélanie Touvrey-Loiodice, Guillaume Mercey, Ludovic Jean

, Pierre-Yves Renard, Florian Nachon

An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice

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Killian Oukoloff, Sovy Chao, Monika Cieslikiewicz-Bouet, Romain Mougeot, Ludovic Jean

, Pierre-Yves Renard

Improved Access to Huprine Derivatives Functionalized at Position 9

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Julien Renou, José Dias

, José Diaz, Guillaume Mercey, Tristan Verdelet, Catherine Rousseau, Anne-Julie Gastellier, Mélanie Arboléas, Mélanie Touvrey, Rachid Baati, Ludovic Jean

, Florian Nachon, Pierre-Yves Renard

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

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All papers authored by Ludovic Jean