Ludovic Jean - Dissemin

Papers authored by Ludovic Jean

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2016 Sovy Chao, Eric Krejci, Véronique Bernard, Jacqueline Leroy, Ludovic Jean

, Pierre-Yves Renard

A selective and sensitive near-infrared fluorescent probe for acetylcholinesterase imaging

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2015 Rómulo Aráoz, Monika Bouet, Manuela Bartolini, Nicolas Coquelle, Jacques-Philippe Colletier, Denis Servent, Jordi Molgo, Ludovic Jean

, Pierre-Yves Renard

Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of α7 nicotinic acetylcholine receptor

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Killian Oukoloff, Monika Cieslikiewicz-Bouet, Sovy Chao, Emilie Costa Branquinho, Cedric Bouteiller, Ludovic Jean

, Pierre-Yves Renard

PET and SPECT Radiotracers for Alzheimer’s Disease

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Killian Oukoloff, Frederic Buron, Sylvain Routier, Ludovic Jean

, Pierre-Yves Renard

Synthetic Route to Rare Isoindolones Derivatives

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2014 Lucie Aliouane, Chao Sovy, Leyre Brizuela, Emmanuel Pfund, Olivier Cuvillier, Ludovic Jean

, Pierre-Yves Renard, Thierry Lequeux

Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1

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Maria Kliachyna, Gianluca Santoni

, Valentin Nussbaum, Julien Renou, Benoît Sanson, Jacques-Philippe Colletier, Mélanie Arboléas, Mélanie Loiodice, Martin Weik, Ludovic Jean

, Pierre-Yves Renard, Florian Nachon, Rachid Baati

Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase.

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Emilia Oueis, Gianluca Santoni

, Cyril Ronco

, Olga Syzgantseva

, Vincent Tognetti, Laurent Joubert, Anthony Romieu, Martin Weik, Ludovic Jean

, Cyrille Sabot, Florian Nachon, Pierre-Yves Renard

Reaction site-driven regioselective synthesis of AChE inhibitors.

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Julien Renou, Mélanie Loiodice, Mélanie Arboléas, Rachid Baati, Ludovic Jean

, Florian Nachon, Pierre-Yves Renard

Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterases

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2013 Florian Nachon, Eugénie Carletti, Cyril Ronco

, Marie Trovaslet, Yvain Nicolet, Ludovic Jean

, Pierre-Yves Renard

Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase.

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Emilie Da Costa Branquinho, Guillaume Becker

, Cédric Bouteiller, Ludovic Jean

, Pierre-Yves Renard, Luc Zimmer

Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase

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Julien Renou, Guillaume Mercey, Tristan Verdelet, Emilia Păunescu, Emilie Gillon, Mélanie Arboléas, Mélanie Loiodice, Maria Kliachyna, Rachid Baati, Florian Nachon, Ludovic Jean

, Pierre-Yves Renard

Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents.

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2012 Xavier Brazzolotto, Marielle Wandhammer, Cyril Ronco

, Marie Trovaslet, Ludovic Jean

, Oksana Lockridge, Pierre-Yves Renard, Florian Nachon

Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure.

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2011 Cyril Ronco

, Eugénie Carletti, Jacques-Philippe Colletier, Martin Weik, Florian Nachon, Ludovic Jean

, Pierre-Yves Renard

Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography.

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Papers authored by Ludovic Jean