All papers authored by Dylan Ryan
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2023
Christian G. Peace 
,
Alexander Hooftman ,
Dylan G. Ryan
,
Alexander Hooftman ,
Dylan G. Ryan
Inflammatory mitochondrial nucleic acids as drivers of pathophysiology
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Alex von Kriegsheim,
Alexander Hooftman ,
Christian G. Peace ,
Dylan G. Ryan ,
Emily A. Day ,
Ming Yang,
Anne F. McGettrick ,
Maureen Yin ,
Montano En,
Erica N. Montano,
Lihong Huo,
Toller Kawahisa Je,
Juliana E. Toller-Kawahisa,
Vincent Zecchini,
Tristram A. J. Ryan
and 18 other authors
,
Christian G. Peace ,
Dylan G. Ryan ,
Emily A. Day ,
Ming Yang,
Anne F. McGettrick ,
Maureen Yin ,
Montano En,
Erica N. Montano,
Lihong Huo,
Toller Kawahisa Je,
Juliana E. Toller-Kawahisa,
Vincent Zecchini,
Tristram A. J. Ryan
and 18 other authors
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
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2022
Marco Sciacovelli,
Aurelien Dugourd,
Lorea Valcarcel Jimenez ,
Ming Yang,
Efterpi Nikitopoulou,
Ana S. H. Costa ,
Laura Tronci,
Veronica Caraffini,
Paulo Rodrigues,
Christina Schmidt ,
Dylan Gerard Ryan ,
Timothy Young,
Vincent R. Zecchini,
Sabrina H. Rossi ,
Charlie Massie
and 13 other authors
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,
Ming Yang,
Efterpi Nikitopoulou,
Ana S. H. Costa ,
Laura Tronci,
Veronica Caraffini,
Paulo Rodrigues,
Christina Schmidt ,
Dylan Gerard Ryan ,
Timothy Young,
Vincent R. Zecchini,
Sabrina H. Rossi ,
Charlie Massie
and 13 other authors
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Mimmi Le Lundahl ,
Morgane Mitermite ,
Dylan Gerard Ryan ,
Sarah Case,
Niamh C. Williams,
Ming Yang,
Roisin I. Lynch,
Eimear Lagan,
Filipa M. Lebre,
Aoife L. Gorman,
Bojan Stojkovic,
Adrian P. Bracken,
Christian Frezza,
Frederick J. Sheedy,
Eoin M. Scanlan
and 3 other authors
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,
Morgane Mitermite ,
Dylan Gerard Ryan ,
Sarah Case,
Niamh C. Williams,
Ming Yang,
Roisin I. Lynch,
Eimear Lagan,
Filipa M. Lebre,
Aoife L. Gorman,
Bojan Stojkovic,
Adrian P. Bracken,
Christian Frezza,
Frederick J. Sheedy,
Eoin M. Scanlan
and 3 other authors
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Dylan G. Ryan ,
Elena V. Knatko,
Alva M. Casey,
Jens L. Hukelmann ,
Sharadha Dayalan Naidu,
Alejandro J. Brenes,
Thanapon Ekkunagul,
Christa Baker,
Maureen Higgins,
Laura Tronci,
Efterpi Nikitopolou,
Tadashi Honda,
Richard C. Hartley,
Luke A. J. O’Neill,
Christian Frezza
and 6 other authors
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,
Elena V. Knatko,
Alva M. Casey,
Jens L. Hukelmann ,
Sharadha Dayalan Naidu,
Alejandro J. Brenes,
Thanapon Ekkunagul,
Christa Baker,
Maureen Higgins,
Laura Tronci,
Efterpi Nikitopolou,
Tadashi Honda,
Richard C. Hartley,
Luke A. J. O’Neill,
Christian Frezza
and 6 other authors
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2021
Dylan Gerard Ryan ,
Ming Yang,
Hiran A. Prag ,
Giovanny Rodriguez Blanco,
Efterpi Nikitopoulou,
Marc Segarra-Mondejar,
Christopher A. Powell ,
Tim Young ,
Nils Burger ,
Jan Lj J. Miljkovic,
Michal Minczuk,
Michael P. Murphy ,
Alex von Kriegsheim,
Christian Frezza
,
Ming Yang,
Hiran A. Prag ,
Giovanny Rodriguez Blanco,
Efterpi Nikitopoulou,
Marc Segarra-Mondejar,
Christopher A. Powell ,
Tim Young ,
Nils Burger ,
Jan Lj J. Miljkovic,
Michal Minczuk,
Michael P. Murphy ,
Alex von Kriegsheim,
Christian Frezza
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
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Dylan Ryan ,
Christian Frezza
,
Christian Frezza
IL-10-Mediated Refueling of Exhausted T Cell Mitochondria Boosts Anti-Tumour Immunity
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Dylan Gerard Ryan ,
Elena V. Knatko,
Alva Casey,
Jens L. Hukelmann ,
Alejandro J. Brenes,
Sharadha Dayalan Naidu,
Sharadha Dayalan Naidu,
Maureen Higgins,
Laura Tronci,
Efterpi Nikitopoulou,
Luke A. J. O’Neill,
Christian Frezza,
Angus I. Lamond,
Andrey Y. Abramov,
Doreen A. Cantrell
and 2 other authors
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,
Elena V. Knatko,
Alva Casey,
Jens L. Hukelmann ,
Alejandro J. Brenes,
Sharadha Dayalan Naidu,
Sharadha Dayalan Naidu,
Maureen Higgins,
Laura Tronci,
Efterpi Nikitopoulou,
Luke A. J. O’Neill,
Christian Frezza,
Angus I. Lamond,
Andrey Y. Abramov,
Doreen A. Cantrell
and 2 other authors
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Zbigniew Zasłona,
Ewelina Flis,
Mieszko M. Wilk ,
Richard G. Carroll ,
Eva M. Palsson-Mcdermott,
Mark M. Hughes,
Ciana Diskin,
Kathy Banahan,
Dylan G. Ryan ,
Alexander Hooftman ,
Alicja Misiak,
Jay Kearney ,
Gunter Lochnit ,
Wilhelm Bertrams ,
Timm Greulich
and 7 other authors
,
Richard G. Carroll ,
Eva M. Palsson-Mcdermott,
Mark M. Hughes,
Ciana Diskin,
Kathy Banahan,
Dylan G. Ryan ,
Alexander Hooftman ,
Alicja Misiak,
Jay Kearney ,
Gunter Lochnit ,
Wilhelm Bertrams ,
Timm Greulich
and 7 other authors
Caspase-11 promotes allergic airway inflammation
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2018
Dylan G. Ryan ,
Michael P. Murphy,
Christian Frezza ,
Hiran A. Prag ,
Edward T. Chouchani,
Luke A. O’Neill,
Evanna L. Mills
,
Michael P. Murphy,
Christian Frezza ,
Hiran A. Prag ,
Edward T. Chouchani,
Luke A. O’Neill,
Evanna L. Mills
Coupling Krebs cycle metabolites to signalling in immunity and cancer
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Jeroen Baardman ,
Verberk Sgs,
Sanne G. S. Verberk,
Michel van Weeghel,
Saskia van der Velden,
Rob C. I. Wüst ,
Dave Speijer,
Maarten E. Witte,
Denis Sw,
Menno P. J. de Winther,
Jan Van den Bossche,
Koen H. M. Prange,
Prange Khm,
Annette E. Neele,
Ryan Dg
and 11 other authors
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,
Verberk Sgs,
Sanne G. S. Verberk,
Michel van Weeghel,
Saskia van der Velden,
Rob C. I. Wüst ,
Dave Speijer,
Maarten E. Witte,
Denis Sw,
Menno P. J. de Winther,
Jan Van den Bossche,
Koen H. M. Prange,
Prange Khm,
Annette E. Neele,
Ryan Dg
and 11 other authors
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David Olagnier ,
Aske M. Brandtoft ,
Camilla Gunderstofte,
Nikolaj L. Villadsen,
Christian Krapp,
Anne L. Thielke,
Anders Laustsen,
Suraj Peri,
Anne Louise Hansen ,
Lene Bonefeld,
Jacob Thyrsted,
Victor Bruun,
Marie B. Iversen,
Lin Lin,
Virginia M. Artegoitia
and 19 other authors
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,
Aske M. Brandtoft ,
Camilla Gunderstofte,
Nikolaj L. Villadsen,
Christian Krapp,
Anne L. Thielke,
Anders Laustsen,
Suraj Peri,
Anne Louise Hansen ,
Lene Bonefeld,
Jacob Thyrsted,
Victor Bruun,
Marie B. Iversen,
Lin Lin,
Virginia M. Artegoitia
and 19 other authors
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James O. Early ,
Deepthi Menon,
Cathy A. Wyse,
Mariana P. Cervantes-Silva,
Zbigniew Zaslona,
Richard G. Carroll ,
Eva M. Palsson-Mcdermott,
Stefano Angiari,
Dylan G. Ryan ,
Sarah E. Corcoran,
George Timmons,
Sarah S. Geiger,
Darren J. Fitzpatrick,
Daniel O’Connell,
Ramnik J. Xavier
and 3 other authors
,
Deepthi Menon,
Cathy A. Wyse,
Mariana P. Cervantes-Silva,
Zbigniew Zaslona,
Richard G. Carroll ,
Eva M. Palsson-Mcdermott,
Stefano Angiari,
Dylan G. Ryan ,
Sarah E. Corcoran,
George Timmons,
Sarah S. Geiger,
Darren J. Fitzpatrick,
Daniel O’Connell,
Ramnik J. Xavier
and 3 other authors
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2
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Evanna L. Mills ,
Dylan G. Ryan ,
Hiran A. Prag ,
Dina Dikovskaya,
Deepthi Menon,
Zbigniew Zaslona,
Mark P. Jedrychowski,
Ana S. H. Costa ,
Maureen Higgins,
Emily Hams,
John Szpyt,
Marah C. Runtsch,
Martin S. King,
Joanna F. McGouran,
Roman Fischer
and 20 other authors
,
Dylan G. Ryan ,
Hiran A. Prag ,
Dina Dikovskaya,
Deepthi Menon,
Zbigniew Zaslona,
Mark P. Jedrychowski,
Ana S. H. Costa ,
Maureen Higgins,
Emily Hams,
John Szpyt,
Marah C. Runtsch,
Martin S. King,
Joanna F. McGouran,
Roman Fischer
and 20 other authors
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
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2017
Dylan Gerard Ryan ,
Luke A. J. O'Neill
,
Luke A. J. O'Neill
Krebs cycle rewired for macrophage and dendritic cell effector functions
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