Hannah L. Woodward - Dissemin

Language
Login

All papers authored by Hannah L. Woodward

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2022 Yuguang Zhao

ORCID

, William Mahy, Nicky J. Willis

ORCID

, Hannah L. Woodward

ORCID

, David Steadman

ORCID

, Elliott D. Bayle, Benjamin N. Atkinson

ORCID

, James Sipthorp, Luca Vecchia, Reinis R. Ruza, Karl Harlos, Fiona Jeganathan, Stefan Constantinou, Artur Costa, Svend Kjær and 6 other authors

Structural Analysis and Development of Notum Fragment Screening Hits

Upload

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Nicky J. Willis

ORCID

, William Mahy, James Sipthorp, Yuguang Zhao

ORCID

, Hannah L. Woodward

ORCID

, Benjamin N. Atkinson

ORCID

, Elliott D. Bayle

ORCID

, Fredrik Svensson

ORCID

, Sarah Frew, Fiona Jeganathan, Amy Monaghan, Stefano Benvegnù, Sarah Jolly, Luca Vecchia, Reinis R. Ruza and 9 other authors

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit

Upload

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2021 Elliott D. Bayle, Fredrik Svensson

ORCID

, Benjamin N. Atkinson, David Steadman

ORCID

, Nicky J. Willis, Hannah L. Woodward

ORCID

, Paul Whiting, Jean-Paul Vincent, Paul V. Fish

ORCID

Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling

Upload

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2020 William Mahy, Nicky J. Willis, Yuguang Zhao

ORCID

, Hannah L. Woodward

ORCID

, Fredrik Svensson

ORCID

, James Sipthorp, Luca Vecchia, Reinis R. Ruza, James Hillier, Svend Kjær, Sarah Frew, Amy Monaghan, Magda Bictash, Patricia C. Salinas, Paul Whiting and 3 other authors

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

Upload

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

William Mahy, Mikesh Patel, David Steadman

ORCID

, Hannah L. Woodward

ORCID

, Benjamin N. Atkinson

ORCID

, Fredrik Svensson

ORCID

, Nicky J. Willis, Alister Flint, Dimitra Papatheodorou, Yuguang Zhao

ORCID

, Luca Vecchia, Reinis R. Ruza, James Hillier, Sarah Frew, Amy Monaghan and 5 other authors

Screening of a custom-designed acid fragment library identifies 1-phenylpyrroles and 1-phenylpyrrolidines as inhibitors of Notum carboxylesterase activity

Upload

This paper is made freely available by the publisher.

Benjamin R. Bellenie

ORCID

, Kwai-Ming J. Cheung, Ana Varela, Olivier A. Pierrat, Gavin W. Collie

ORCID

, Gary M. Box, Michael D. Bright, Sharon Gowan, Angela Hayes, Matthew J. Rodrigues, Kartika N. Shetty, Michael Carter, Owen A. Davis, Alan T. Henley, Paolo Innocenti and 15 other authors

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

Download from pubs.acs.org

This paper is made freely available by the publisher.

2019 Simon J. Anderhub, Grace Wing-Yan Mak, Mark D. Gurden, Amir Faisal

ORCID

, Konstantinos Drosopoulos, Katie Walsh, Hannah L. Woodward

ORCID

, Paolo Innocenti, Isaac M. Westwood, Sébastien Naud, Angela Hayes, Efthymia Theofani, Simone Filosto, Harry Saville, Rosemary Burke and 6 other authors

High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers

Download from aacrjournals.org

This paper is made freely available by the publisher.

2018 Hannah L. Woodward

ORCID

, Paolo Innocenti, Kwai-Ming J. Cheung, Angela Hayes, Jennie Roberts, Alan T. Henley, Amir Faisal, Grace Wing-Yan Mak, Gary Box, Isaac M. Westwood, Nora Cronin, Michael Carter, Melanie Valenti, Alexis De Haven Brandon, Lisa O’Fee and 10 other authors

Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4-d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine (BOS172722)

Download from pubs.acs.org

This paper is made freely available by the publisher.

2017 Amir Faisal, Grace W. Y. Mak, Mark D. Gurden, Cristina P. R. Xavier, Simon J. Anderhub, Paolo Innocenti, Isaac M. Westwood, Sébastien Naud, Angela Hayes, Gary Box, Melanie R. Valenti, Alexis K. De Haven Brandon, Lisa O'Fee, Jessica Schmitt, Hannah L. Woodward

ORCID

and 7 other authors

Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy

Download from www.nature.com

This paper is made freely available by the publisher.

Benjamin N. Atkinson

ORCID

, Hannah L. Woodward

ORCID

, James Sipthorp

ORCID

ORCID

Regioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives

Download from doi.org

This paper was not found in any repository, but could be made available legally by the author.

2016 Paolo Innocenti, Hannah L. Woodward

ORCID

, Savade Solanki, Sébastien Naud, Isaac M. Westwood, Nora Cronin, Angela Hayes, Jennie Roberts, Alan T. Henley, Ross Baker, Amir Faisal, Grace Wing-Yan Mak, Gary Box, Melanie Valenti, Alexis De Haven Brandon and 11 other authors

Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach

Upload

This paper was not found in any repository, but could be made available legally by the author.

2014 Paolo Innocenti, Hannah Woodward

ORCID

, Lisa O'Fee, Swen Hoelder

Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: Synthesis and modification of pyrido[3,4-d]pyrimidines

Upload

This paper is available in a repository.

2013 Lewis R. Vidler, Panagis Filippakopoulos, Oleg Fedorov, Sarah Picaud, Sarah Martin, Michael Tomsett, Hannah Woodward

ORCID

, Nathan Brown, Stefan Knapp, Swen Hoelder

Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

Download from doi.org

This paper is made freely available by the publisher.

David Benito-Alifonso, Rachel A. Jones, Anh-Tuan Tran, Hannah Woodward

ORCID

, Nichola Smith, M. Carmen Galan

ORCID

Synthesis of mucin-type O-glycan probes as aminopropyl glycosides

Download from doi.org

This paper was not found in any repository, but could be made available legally by the author.

2010 Timothy Gallagher, Hannah Woodward

ORCID

, Nichola Smith

exo-Glycals: Intermediates in the Synthesis of 1,1-Disubstituted C-Glycosides

Upload

This paper was not found in any repository, but could be made available legally by the author.

David Beattie, Andrew Brearley, Zarin Brown, Steven J. Charlton, Brian Cox, Robin A. Fairhurst, John R. Fozard, Peter Gedeck, Paul Kirkham, Koremu Meja, Lana Nanson, James Neef, Helen Oakman, Gillian Spooner, Roger J. Taylor and 3 other authors

Synthesis and evaluation of two series of 4′-aza-carbocyclic nucleosides as adenosine A2A receptor agonists

Upload

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2007 John F. Bower, Andrew J. Williams, Hannah L. Woodward

ORCID

, Peter Szeto, Ron M. Lawrence, Timothy Gallagher

Reactivity of Cyclic Sulfamidates Towards Phosphonate-Stabilized Enolates: Synthesis and Applications of α-Phosphono Lactams.

Upload

This paper was not found in any repository, but could be made available legally by the author.

John F. Bower, Andrew J. Williams, Hannah L. Woodward

ORCID

, Peter Szeto, Ron M. Lawrence, Timothy Gallagher

Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of α-phosphono lactams

Upload

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

1970 Paul Fish, William Mahy, Hannah L. Woodward

ORCID

, Benjamin Atkinson, Elliott D. Bayle, James Sipthorp, Yvonne Jones, Yuguang Zhao, Luca Vecchia, Reinis Reinholds

Inhibitors of secreted carboxy esterase, Notum, and their use in increasing Wnt protein signalling and treatment of central nervous system and other disorders

Upload

Missing publications? Search for publications with a matching author name.