All papers authored by James MacRae
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Khiem C. Lam ,
Kok Haw Jonathan Lim ,
Ana Cardoso ,
Cécile Piot ,
Probir Chakravarty ,
Sonja Blasche ,
Swara Patel ,
Adi Biram ,
Tomas Castro-Dopico ,
Michael D. Buck ,
Richard R. Rodrigues ,
Gry Juul Poulsen ,
Susana A. Palma-Duran
and 24 other authors
Vitamin D regulates microbiome-dependent cancer immunity
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Lesley Vanes,
Serena Melgrati,
Joshua Biggs O’May,
Darryl Hayward,
Paul C. Driscoll ,
Jason Day ,
Alexander Griffiths,
Renata Magueta,
Alexander Morrell ,
James I. MacRae ,
Robert Köchl,
Victor L. J. Tybulewicz
T cell migration requires ion and water influx to regulate actin polymerization
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Simone Kunzelmann ,
Andrew G. Purkiss ,
Mariana Silva Dos Santos ,
James I. MacRae ,
Ian A. Taylor ,
Kasper Fugger ,
Stephen C. West
Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1
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Tiaan Heunis ,
Enrica Pellegrino,
Elliott M. Bernard ,
Nourdine Bah,
Mariana Silva Dos Santos ,
Pierre Santucci,
Beren Aylan ,
Angela Rodgers,
Antony Fearns,
Julia Mitschke,
Christopher Moore ,
James I. MacRae ,
Maria Greco,
Thomas Reinheckel
and 2 other authors
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Natalie Bevan,
Patrícia M. Nunes,
Sebastien Campos,
Mariana Silva dos Santos ,
Emma Sherriff,
James I. MacRae ,
David House,
Dimitrios Anastasiou
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Ryan L. Shearer,
Hamish W. King ,
Katarina Kluckova,
Eric C. Cheung,
Andrew J. Clear ,
Arief S. Gunawan ,
Lingling Zhang,
Louisa K. James ,
James I. MacRae ,
John G. Gribben,
Dinis P. Calado
and 2 other authors
PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma
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Veera Panova ,
Laura Doglio,
Anastasiya Kazachenka,
Georgina Cornish,
Joanna Kirkpatrick,
Jan Attig ,
George R. Young ,
Kevin Litchfield ,
Tom Lesluyes ,
Peter Van Loo ,
Charles Swanton ,
James MacRae ,
Thomas Tüting ,
George Kassiotis
E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion
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Valerie E. Pye ,
Carl Graham,
Luke Muir ,
Jeffrey Seow ,
Kevin W. Ng ,
Nicola J. Cook ,
Chloe Rees-Spear ,
Eleanor Parker,
Mariana Silva dos Santos,
Mariana Silva dos Santos ,
Carolina Rosadas ,
Alberto Susana,
Hefin Rhys,
Andrea Nans
and 26 other authors
SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity
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Ilirjana Bajrami ,
Mariana Silva Dos Santos ,
Sarah Jane Young ,
Simone Kunzelmann ,
Geoff Kelly ,
Graeme Hewitt,
Harshil Patel ,
Robert Goldstone,
Thomas Carell ,
Simon J. Boulton ,
James MacRae ,
Ian A. Taylor ,
Stephen C. West
Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors
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Lee R. Haines,
Aitor Casas-Sánchez ,
Vincent Owino Adung’a ,
Raquel J. Vionette-Amaral,
Shannon Quek ,
Clair Rose ,
Mariana Silva dos Santos ,
Natalia García Escude ,
Hanafy M. Ismail ,
Mark I. Paine,
Seth M. Barribeau,
Simon Wagstaff ,
James I. MacRae ,
Daniel Masiga
and 3 other authors
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
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Guillaume Rey ,
Sandipan Ray,
Pawan K. Jha ,
Paul C. Driscoll ,
Mariana Silva Dos Santos ,
Dania M. Malik,
Radoslaw Lach,
Aalim M. Weljie,
James I. MacRae ,
Utham K. Valekunja ,
Akhilesh B. Reddy
Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
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Nathalie Legrave,
Laura Novellasdemunt ,
Chencheng Xie,
Mark Charles,
Zena Wilson,
Neil P. Jones ,
Stephen Rayport ,
Manuel Rodríguez-Justo,
Vivian Li ,
James I. MacRae ,
Nissim Hay,
Xin Chen
and 1 other authors
Identifying strategies to target the metabolic flexibility of tumours
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Rute M. M. Ferreira,
Jorge Almagro ,
Theodore Evan ,
Nathalie Legrave,
May Zaw Thin,
David Frith,
Joana Carvalho,
David J. Barry ,
Ambrosius P. Snijders ,
Eleanor Herbert,
Emma L. Nye,
James I. MacRae ,
Axel Behrens
CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth
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Paul C. Driscoll ,
Fiona Grimm ,
Aakriti Jain ,
Patrícia M. Nunes,
Michalis Gounis ,
Ginevra Doglioni,
George Papageorgiou ,
Timothy J. Ragan,
Sebastien Campos,
Mariana Silva dos Santos ,
James I. MacRae ,
Nicola O’Reilly ,
Alan J. Wright,
Cyril H. Benes
and 3 other authors
Author Correction: MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG
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Maria Rohm ,
Martijn van de Bunt,
Melissa F. Brereton,
Andrei I. Tarasov ,
Thomas S. Blacker,
Gregor Sachse ,
Mariana Silva dos Santos ,
Raul Terron Exposito,
Simon Davis,
Otto Baba,
Roman Fischer ,
Michael R. Duchen ,
Patrik Rorsman ,
James I. MacRae
and 1 other authors
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells
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