Volker Manfred Arlt

All papers authored by Volker Manfred Arlt

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2021 Helena Dračínská

, Radek Indra

, Sandra Jelínková, Věra Černá

, Volker Arlt

, Marie Stiborová

Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes

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2020 Lisa Hölzl-Armstrong, Jill E. Kucab, Sarah Moody, Edwin P. Zwart, Lucie Loutkotová, Veronica Duffy, Mirjam Luijten

, Gonçalo Gamboa da Costa, Michael R. Stratton, David H. Phillips, Volker M. Arlt

Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts

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Radek Indra

, Petr Pompach, Katarína Vavrová

, Kateřina Jáklová, Zbyněk Heger, Vojtěch Adam, Tomáš Eckschlager, Kateřina Kopečková, Volker Manfred Arlt

, Marie Stiborová

Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems

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2019 Mateja Sborchia, Eric G. De Prez, Marie-Hélène Antoine, Lucie Bienfait, Radek Indra

, Gabriel Valbuena, David H. Phillips, Joëlle L. Nortier, Marie Stiborová, Hector C. Keun, Volker M. Arlt

The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro

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Radek Indra

, Petr Pompach, Václav Martínek

, Paulína Takácsová, Katarína Vavrová

, Zbyněk Heger, Vojtěch Adam, Tomáš Eckschlager, Kateřina Kopečková, Volker Manfred Arlt

, Marie Stiborová

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation

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Lindsay Reed, Radek Indra

, Iveta Mrizova, Michaela Moserova, Heinz H. Schmeiser, C. Roland Wolf, Colin J. Henderson, Marie Stiborova, David H. Phillips, Volker M. Arlt

Application of hepatic cytochrome b/P450 reductase null (HBRN) mice to study the role of cytochrome b in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

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2018 Simon C. Baker

, Volker M. Arlt

, Radek Indra

, Madeleine Joel, Marie Stiborová

, Ian Eardley, Niaz Ahmad, Wolfgang Otto

, Maximilian Burger, Peter Rubenwolf

, David H. Phillips

, Jennifer Southgate

Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of “luminal” muscle-invasive bladder cancers

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Lindsay Reed, Iveta Mrizova, Frantisek Barta, Radek Indra

, Michaela Moserova, Klaus Kopka, Heinz H. Schmeiser, C. Roland Wolf, Colin J. Henderson, Marie Stiborova, David H. Phillips

, Volker M. Arlt

Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice

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All papers authored by Volker Manfred Arlt