Papers authored by Costas Lyssiotis
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Andrew J. Schwartz,
Joshua W. Goyert 
,
Sumeet Solanki,
Samuel A. Kerk ,
Brandon Chen ,
Cristina Castillo,
Peggy P. Hsu,
Brian T. Do ,
Rashi Singhal ,
Michael K. Dame ,
Ho-Joon Lee ,
Jason R. Spence,
Samira Lakhal-Littleton,
Matthew G. Vander Heiden ,
Costas A. Lyssiotis
and 2 other authors
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,
Sumeet Solanki,
Samuel A. Kerk ,
Brandon Chen ,
Cristina Castillo,
Peggy P. Hsu,
Brian T. Do ,
Rashi Singhal ,
Michael K. Dame ,
Ho-Joon Lee ,
Jason R. Spence,
Samira Lakhal-Littleton,
Matthew G. Vander Heiden ,
Costas A. Lyssiotis
and 2 other authors
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Samantha N. Devenport,
Rashi Singhal ,
Megan D. Radyk,
Joseph G. Taranto ,
Samuel A. Kerk ,
Brandon Chen ,
Joshua W. Goyert ,
Chesta Jain,
Nupur K. Das ,
Katherine Oravecz-Wilson,
Li Zhang,
Joel K. Greenson,
Y. Eugene Chen ,
Scott A. Soleimanpour ,
Pavan Reddy
and 2 other authors
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,
Megan D. Radyk,
Joseph G. Taranto ,
Samuel A. Kerk ,
Brandon Chen ,
Joshua W. Goyert ,
Chesta Jain,
Nupur K. Das ,
Katherine Oravecz-Wilson,
Li Zhang,
Joel K. Greenson,
Y. Eugene Chen ,
Scott A. Soleimanpour ,
Pavan Reddy
and 2 other authors
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Rashi Singhal ,
Sreedhar R. Mitta,
Nupur K. Das ,
Samuel A. Kerk ,
Peter Sajjakulnukit ,
Sumeet Solanki,
Anthony Andren ,
Roshan Kumar ,
Kenneth P. Olive ,
Ruma Banerjee ,
Costas A. Lyssiotis ,
Yatrik M. Shah
,
Sreedhar R. Mitta,
Nupur K. Das ,
Samuel A. Kerk ,
Peter Sajjakulnukit ,
Sumeet Solanki,
Anthony Andren ,
Roshan Kumar ,
Kenneth P. Olive ,
Ruma Banerjee ,
Costas A. Lyssiotis ,
Yatrik M. Shah
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron
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William Giblin ,
Mary E. Skinner ,
Li Zhang,
Sophie Trefely,
Erika L. Varner,
Min Wang,
James S. Wilmott,
H. Peter Soyer ,
Richard A. Sturm ,
Mitchell S. Stark ,
Monique E. Verhaegen,
Nathaniel W. Snyder ,
Lauren Bringman-Rodenbarger,
Angela H. Guo,
Surinder Kumar
and 22 other authors
,
Mary E. Skinner ,
Li Zhang,
Sophie Trefely,
Erika L. Varner,
Min Wang,
James S. Wilmott,
H. Peter Soyer ,
Richard A. Sturm ,
Mitchell S. Stark ,
Monique E. Verhaegen,
Nathaniel W. Snyder ,
Lauren Bringman-Rodenbarger,
Angela H. Guo,
Surinder Kumar
and 22 other authors
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
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Samantha B. Kemp,
Eileen S. Carpenter,
Nina G. Steele,
Katelyn L. Donahue ,
Zeribe C. Nwosu ,
Amanda Pacheco ,
Ashley Velez-Delgado,
Rosa E. Menjivar,
Fatima Lima,
Stephanie The,
Carlos E. Espinoza,
Kristee Brown,
Daniel Long,
Costas A. Lyssiotis ,
Arvind Rao
and 3 other authors
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,
Zeribe C. Nwosu ,
Amanda Pacheco ,
Ashley Velez-Delgado,
Rosa E. Menjivar,
Fatima Lima,
Stephanie The,
Carlos E. Espinoza,
Kristee Brown,
Daniel Long,
Costas A. Lyssiotis ,
Arvind Rao
and 3 other authors
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Francesca Puca,
Fei Yu,
Caterina Bartolacci ,
Piergiorgio Pettazzoni,
Alessandro Carugo ,
Emmet Huang-Hobbs ,
Jintan Liu ,
Ciro Zanca,
Federica Carbone ,
Edoardo Del Poggetto,
Joy Gumin,
Pushan Dasgupta ,
Sahil Seth ,
Sanjana Srinivasan,
Frederick F. Lang
and 14 other authors
,
Piergiorgio Pettazzoni,
Alessandro Carugo ,
Emmet Huang-Hobbs ,
Jintan Liu ,
Ciro Zanca,
Federica Carbone ,
Edoardo Del Poggetto,
Joy Gumin,
Pushan Dasgupta ,
Sahil Seth ,
Sanjana Srinivasan,
Frederick F. Lang
and 14 other authors
Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma
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Samantha B. Kemp,
Nina G. Steele,
Eileen S. Carpenter,
Katelyn L. Donahue,
Grace G. Bushnell,
Aaron H. Morris,
Stephanie The,
Sophia M. Orbach,
Veerin R. Sirihorachai,
Zeribe C. Nwosu ,
Carlos Espinoza,
Fatima Lima,
Kristee Brown,
Alexander A. Girgis ,
Valerie Gunchick
and 9 other authors
,
Carlos Espinoza,
Fatima Lima,
Kristee Brown,
Alexander A. Girgis ,
Valerie Gunchick
and 9 other authors
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages
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Jennifer A. Jiménez ,
April A. Apfelbaum ,
Allegra G. Hawkins,
Laurie K. Svoboda ,
Abhijay Kumar,
Ramon Ocadiz Ruiz ,
Alessandra X. Garcia,
Elena Haarer,
Zeribe C. Nwosu ,
Joshua Bradin ,
Trupta Purohit,
Dong Chen,
Tomasz Cierpicki,
Jolanta Grembecka,
Costas A. Lyssiotis
and 1 other authors
,
April A. Apfelbaum ,
Allegra G. Hawkins,
Laurie K. Svoboda ,
Abhijay Kumar,
Ramon Ocadiz Ruiz ,
Alessandra X. Garcia,
Elena Haarer,
Zeribe C. Nwosu ,
Joshua Bradin ,
Trupta Purohit,
Dong Chen,
Tomasz Cierpicki,
Jolanta Grembecka,
Costas A. Lyssiotis
and 1 other authors
EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma
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Nina G. Steele,
Giulia Biffi ,
Samantha B. Kemp,
Yaqing Zhang,
Donovan Drouillard,
Li-Jyun Syu,
Yuan Hao,
Tobiloba E. Oni,
Erin Brosnan,
Ela Elyada,
Abhishek Doshi ,
Christa Hansma,
Carlos Espinoza,
Ahmed Abbas,
Stephanie The
and 21 other authors
,
Samantha B. Kemp,
Yaqing Zhang,
Donovan Drouillard,
Li-Jyun Syu,
Yuan Hao,
Tobiloba E. Oni,
Erin Brosnan,
Ela Elyada,
Abhishek Doshi ,
Christa Hansma,
Carlos Espinoza,
Ahmed Abbas,
Stephanie The
and 21 other authors
Inhibition of Hedgehog signaling alters fibroblast composition in pancreatic cancer
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2020
Yingjie Bian ,
Wei Li,
Daniel M. Kremer ,
Peter Sajjakulnukit ,
Shasha Li,
Joel Crespo,
Zeribe C. Nwosu ,
Li Zhang,
Arkadiusz Czerwonka,
Anna Pawłowska ,
Houjun Xia,
Jing Li,
Peng Liao ,
Jiali Yu,
Linda Vatan
and 14 other authors
,
Wei Li,
Daniel M. Kremer ,
Peter Sajjakulnukit ,
Shasha Li,
Joel Crespo,
Zeribe C. Nwosu ,
Li Zhang,
Arkadiusz Czerwonka,
Anna Pawłowska ,
Houjun Xia,
Jing Li,
Peng Liao ,
Jiali Yu,
Linda Vatan
and 14 other authors
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
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Kirsten L. Bryant ,
Clint A. Stalnecker ,
Daniel Zeitouni,
Jennifer E. Klomp,
Sen Peng,
Andrey P. Tikunov,
Venugopal Gunda,
Mariaelena Pierobon,
Andrew M. Waters ,
Samuel D. George,
Garima Tomar,
Björn Papke ,
G. Aaron Hobbs ,
Liang Yan,
Tikvah K. Hayes
and 16 other authors
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,
Clint A. Stalnecker ,
Daniel Zeitouni,
Jennifer E. Klomp,
Sen Peng,
Andrey P. Tikunov,
Venugopal Gunda,
Mariaelena Pierobon,
Andrew M. Waters ,
Samuel D. George,
Garima Tomar,
Björn Papke ,
G. Aaron Hobbs ,
Liang Yan,
Tikvah K. Hayes
and 16 other authors
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Andrew Charles Little ,
Ilya Kovalenko,
Laura Elaine Goo,
Hanna Sungok Hong,
Samuel Andrew Kerk ,
Joel Anthony Yates ,
Vinee Purohit ,
David Benner Lombard,
Sofia Diana Merajver,
Costas Andreas Lyssiotis
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,
Ilya Kovalenko,
Laura Elaine Goo,
Hanna Sungok Hong,
Samuel Andrew Kerk ,
Joel Anthony Yates ,
Vinee Purohit ,
David Benner Lombard,
Sofia Diana Merajver,
Costas Andreas Lyssiotis
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Michael A. Badgley ,
Daniel M. Kremer ,
H. Carlo Maurer ,
Kathleen E. DelGiorno ,
Ho-Joon Lee ,
Vinee Purohit ,
Irina R. Sagalovskiy ,
Alice Ma ,
Jonathan Kapilian ,
Christina E. M. Firl,
Amanda R. Decker ,
Steve A. Sastra ,
Carmine F. Palermo,
Leonardo R. Andrade ,
Peter Sajjakulnukit
and 15 other authors
,
Daniel M. Kremer ,
H. Carlo Maurer ,
Kathleen E. DelGiorno ,
Ho-Joon Lee ,
Vinee Purohit ,
Irina R. Sagalovskiy ,
Alice Ma ,
Jonathan Kapilian ,
Christina E. M. Firl,
Amanda R. Decker ,
Steve A. Sastra ,
Carmine F. Palermo,
Leonardo R. Andrade ,
Peter Sajjakulnukit
and 15 other authors
Cysteine depletion induces pancreatic tumor ferroptosis in mice
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Zhangsen Zhou ,
Mauricio Torres ,
Haibo Sha,
Christopher J. Halbrook ,
Françoise Van den Bergh ,
Rachel B. Reinert ,
Tatsuya Yamada,
Siwen Wang ,
Yingying Luo ,
Allen H. Hunter ,
Chunqing Wang ,
Thomas H. Sanderson ,
Meilian Liu ,
Aaron Taylor ,
Hiromi Sesaki
and 5 other authors
,
Mauricio Torres ,
Haibo Sha,
Christopher J. Halbrook ,
Françoise Van den Bergh ,
Rachel B. Reinert ,
Tatsuya Yamada,
Siwen Wang ,
Yingying Luo ,
Allen H. Hunter ,
Chunqing Wang ,
Thomas H. Sanderson ,
Meilian Liu ,
Aaron Taylor ,
Hiromi Sesaki
and 5 other authors
Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes
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Yaqing Zhang ,
Jenny Lazarus,
Nina G. Steele,
Wei Yan,
Ho-Joon Lee ,
Zeribe C. Nwosu ,
Christopher J. Halbrook ,
Rosa E. Menjivar,
Samantha B. Kemp,
Veerin R. Sirihorachai,
Ashley Velez-Delgado,
Katelyn Donahue,
Eileen S. Carpenter,
Kristee L. Brown,
Valerie Irizarry-Negron
and 8 other authors
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,
Jenny Lazarus,
Nina G. Steele,
Wei Yan,
Ho-Joon Lee ,
Zeribe C. Nwosu ,
Christopher J. Halbrook ,
Rosa E. Menjivar,
Samantha B. Kemp,
Veerin R. Sirihorachai,
Ashley Velez-Delgado,
Katelyn Donahue,
Eileen S. Carpenter,
Kristee L. Brown,
Valerie Irizarry-Negron
and 8 other authors
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Barbara S. Nelson,
Lin Lin,
Daniel M. Kremer,
Cristovão M. Sousa,
Cecilia Cotta-Ramusino,
Amy Myers,
Johanna Ramos,
Tina Gao,
Ilya Kovalenko,
Kari Wilder-Romans,
Joseph Dresser,
Mary Davis,
Ho-Joon Lee,
Zeribe C. Nwosu ,
Scott Campit
and 11 other authors
,
Scott Campit
and 11 other authors
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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2019
Evandro F. Fang ,
Yujun Hou ,
Sofie Lautrup ,
Martin Borch Jensen,
Beimeng Yang,
Tanima SenGupta,
Domenica Caponio ,
Rojyar Khezri,
Tyler G. Demarest,
Yahyah Aman,
David Figueroa,
Marya Morevati,
Ho-Joon Lee ,
Hisaya Kato ,
Henok Kassahun
and 14 other authors
,
Yujun Hou ,
Sofie Lautrup ,
Martin Borch Jensen,
Beimeng Yang,
Tanima SenGupta,
Domenica Caponio ,
Rojyar Khezri,
Tyler G. Demarest,
Yahyah Aman,
David Figueroa,
Marya Morevati,
Ho-Joon Lee ,
Hisaya Kato ,
Henok Kassahun
and 14 other authors
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
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Kirsten L. Bryant ,
Clint A. Stalnecker ,
Daniel Zeitouni,
Jennifer E. Klomp ,
Sen Peng,
Andrey P. Tikunov,
Venugopal Gunda,
Mariaelena Pierobon,
Andrew M. Waters ,
Samuel D. George,
Garima Tomar,
Björn Papke ,
G. Aaron Hobbs ,
Liang Yan,
Tikvah K. Hayes
and 16 other authors
,
Clint A. Stalnecker ,
Daniel Zeitouni,
Jennifer E. Klomp ,
Sen Peng,
Andrey P. Tikunov,
Venugopal Gunda,
Mariaelena Pierobon,
Andrew M. Waters ,
Samuel D. George,
Garima Tomar,
Björn Papke ,
G. Aaron Hobbs ,
Liang Yan,
Tikvah K. Hayes
and 16 other authors
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
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