Published in
Royal Society of Chemistry, Analytical Methods, 35(9), p. 5174-5180, 2017
DOI: 10.1039/c7ay01433c
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Characterization of phenolic acids binding to thrombin using frontal affinity chromatography and molecular docking
Journal article published in 2017 by
Yu-Xiu Yang,
Su-Ying Li,
Qian Zhang,
Hua Chen,
Zhi-Ning Xia,
Feng-Qing Yang 
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Abstract
The thrombin was simply immobilized by IAM chromatography column, and the binding parameters for phenolic acids binding to thrombin were determined by frontal affinity chromatography. The Autodock software was adopted to study the binding model between phenolic acids and thrombin.