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Royal Society of Chemistry, Chemical Communications, 28(54), p. 3440-3443, 2018

DOI: 10.1039/c8cc00221e

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Membrane bound COMT isoform is an interfacial enzyme: general mechanism and new drug design paradigm

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We have determined the substrate differentiation mechanism between the membrane bound and water soluble isoforms of important drug target catechol-O-methyltransferase.