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American Association for the Advancement of Science, Science Signaling, 436(9), 2016

DOI: 10.1126/scisignal.aaf0891

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Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway

Journal article published in 2016 by Tujin Shi, Mario Niepel, Jason E. McDermott ORCID, Yuqian Gao, Carrie D. Nicora, William B. Chrisler, Lye M. Markillie, Vladislav A. Petyuk, Richard D. Smith, Karin D. Rodland, Peter K. Sorger ORCID, Wei-Jun Qian, H. Steven Wiley
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abundance of most EGFR-MAPK pathway proteins is conserved across cell types, revealing adaptors as rate-limiting nodes.