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All papers authored by Peter K. Sorger

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2021 Denis Schapiro, Artem Sokolov

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, Clarence Yapp

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, Yu-An Chen, Jeremy L. Muhlich

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, Allison L. Creason

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, Ajit J. Nirmal, Gregory J. Baker

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, Maulik K. Nariya, Jia-Ren Lin

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, Zoltan Maliga, Connor A. Jacobson

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, Matthew W. Hodgman, Juha Ruokonen and 12 other authors

MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

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Baishan Jiang

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, Yang Gao, Jianwei Che

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, Ines H. Kaltheuner, Ruben Dries

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, Marian Kalocsay

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, Matthew J. Berberich, Jie Jiang, Inchul You, Nicholas Kwiatkowski, Kristin M. Riching, Danette L. Daniels

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, Peter K. Sorger

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, Matthias Geyer and 2 other authors

Discovery and resistance mechanism of a selective CDK12 degrader

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2020 Anita K. Mehta, Emily M. Cheney, Christina A. Hartl, Constantia Pantelidou

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, Madisson Oliwa, Jessica A. Castrillon, Jia-Ren Lin

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, Katie E. Hurst, Mateus de Oliveira Taveira

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, Nathan T. Johnson

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, William M. Oldham

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, Marian Kalocsay

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, Matthew J. Berberich, Sarah A. Boswell

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, Aditi Kothari and 13 other authors

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

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Robert Krueger, Johanna Beyer, Won-Dong Jang, Nam Wook Kim, Artem Sokolov, Peter K. Sorger

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, Hanspeter Pfister

Facetto: Combining Unsupervised and Supervised Learning for Hierarchical Phenotype Analysis in Multi-Channel Image Data

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2019 Johannes C. Melms, Sreeram Vallabhaneni, Caitlin E. Mills

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, Clarence Yapp

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, Eugenio Morelli

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, Patricia Waszyk

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, Sushil Kumar, Derrick Deming, Nienke Moret

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, Steven Rodriguez, Kartik Subramanian, Meri Rogava, Adam N. R. Cartwright, Adrienne Luoma and 9 other authors

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity

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Shu Wang

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, Eduardo D. Sontag

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, Peter K. Sorger

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Inferring reaction network structure from single-cell, multiplex data, using toric systems theory

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Ziming Du, Jia-Ren Lin

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, Rumana Rashid, Zoltan Maliga, Shu Wang, Jon C. Aster, Benjamin Izar, Peter K. Sorger

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, Sandro Santagata

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Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging

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Marc Hafner

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, Caitlin E. Mills, Kartik Subramanian, Chen Chen, Mirra Chung, Sarah A. Boswell, Robert A. Everley, Changchang Liu, Charlotte S. Walmsley, Dejan Juric, Peter K. Sorger

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Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

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Kartik Subramanian, Elizabeth H. Williams, Mario Niepel, Clive N. Svendsen, Caitlin E. Mills, Marc Hafner, Mills Ce, Anne Marie Barrette

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, Alan D. Stern, K. Subramanian, Mirra Chung, James E. Korkola, Joe W. Gray, Benjamin Gaudio, Williams Eh and 29 other authors

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

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Fleur M. Ferguson

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, Zainab M. Doctor, Scott B. Ficarro, Christopher M. Browne, Jarrod A. Marto, Jared L. Johnson, Tomer M. Yaron, Lewis C. Cantley, Nam Doo Kim, Taebo Sim, Matthew J. Berberich, Marian Kalocsay, Peter K. Sorger

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, Nathanael S. Gray

Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity

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Suman Rao, Deepak Gurbani, Guangyan Du, Robert A. Everley, Christopher M. Browne, Apirat Chaikuad, Li Tan, Martin Schröder, Sudershan Gondi, Scott B. Ficarro, Taebo Sim, Nam Doo Kim, Matthew J. Berberich, Stefan Knapp, Jarrod A. Marto and 3 other authors

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome

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Petar V. Todorov, Benjamin M. Gyori, John A. Bachman

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, Peter K. Sorger

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INDRA-IPM: interactive pathway modeling using natural language with automated assembly

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Huan Wang, Robert P. Sheehan, Adam C. Palmer, Robert A. Everley, Sarah A. Boswell, Noga Ron-Harel, Alison E. Ringel, Kristina M. Holton, Connor A. Jacobson, Alison R. Erickson, Laura Maliszewski, Marcia C. Haigis, Peter K. Sorger

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Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming

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Suman Rao, Guangyan Du, Marc Hafner

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, Kartik Subramanian, Peter K. Sorger

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, Nathanael S. Gray

A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers

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Suthee Rapisuwon

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, Benjamin Izar, Cory Batenchuk, Alexandre Avila, Shaolin Mei, Peter Sorger

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, Jerry M. Parks, Sarah J. Cooper, David Wagner, Jay C. Zeck, Aline J. Charabaty, Michael B. Atkins

Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors

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Calla M. Olson, Yanke Liang, Alan Leggett, Woojun D. Park, Lianbo Li, Caitlin E. Mills, Selma Z. Elsarrag, Scott B. Ficarro, Tinghu Zhang, Robert Düster, Matthias Geyer, Taebo Sim, Jarrod A. Marto, Peter K. Sorger

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, Ken D. Westover and 3 other authors

Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype

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2018 Livnat Jerby-Arnon, Parin Shah, Michael S. Cuoco, Christopher Rodman, Mei-Ju Su, Johannes C. Melms, Rachel Leeson, Abhay Kanodia, Shaolin Mei, Jia-Ren Lin, Shu Wang, Bokang Rabasha, David Liu, Gao Zhang, Claire Margolais and 37 other authors

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

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Nienke Moret

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, Nicholas A. Clark

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, Yuan Wang, Eugen Lounkine, Mario Medvedovic, Jinhua Wang, Nathanael Gray, Jeremy Jenkins

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, Peter K. Sorger

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Cheminformatics tools for analyzing and designing optimized small molecule libraries

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Somponnat Sampattavanich, Bernhard Steiert, Bernhard A. Kramer, Benjamin M. Gyori, John G. Albeck, Peter K. Sorger

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Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases

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