Published in
Royal Society of Chemistry, Dalton Transactions, 33(45), p. 13025-13033, 2016
DOI: 10.1039/c6dt00871b
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Towards99mTc-based imaging agents with effective doxorubicin mimetics: a molecular and cellular study
Journal article published in 2016 by
S. Imstepf,
V. Pierroz,
P. Raposinho,
M. Felber,
T. Fox,
C. Fernandes,
G. Gasser,
I. R. Santos 
,
R. Alberto
,
R. Alberto
This paper is made freely available by the publisher.
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Abstract
99mTc and Re conjugates of Doxorubicin accumulate in the nucleus, bind tightly to DNA and retain hTopoII inhibition.