Published in
Royal Society of Chemistry, Dalton Transactions, 35(45), p. 13671-13674
DOI: 10.1039/c6dt02456d
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Investigation of cobalt(iii)-triazole systems as prototypes for hypoxia-activated drug delivery
Journal article published in 2016 by
Isabela Cristina Aguiar de Souza,
Leticia Villafranca Faro 
,
Carlos Basilio Pinheiro,
Daniel Tadeu Gomes Gonzaga,
Fernando de Carvalho da Silva ,
Vitor Francisco Ferreira ,
Fabio da Silva Miranda,
Marciela Scarpellini,
Mauricio Lanznaster
,
Carlos Basilio Pinheiro,
Daniel Tadeu Gomes Gonzaga,
Fernando de Carvalho da Silva ,
Vitor Francisco Ferreira ,
Fabio da Silva Miranda,
Marciela Scarpellini,
Mauricio Lanznaster
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Abstract
A novel cobalt(iii)-triazole system was developed for hypoxia-activated drug delivery with an [O2]-dependent reduction to cobalt(ii) followed by ligand dissociation.