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Royal Society of Chemistry, MedChemComm, 5(1), p. 345
DOI: 10.1039/c0md00093k
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The kinetics of bulk hydration of the disaccharides α-lactose and trehalose by in situ neutron powder diffraction
Journal article published in 2010 by
Valeska P. Ting 
,
Paul F. Henry,
Marc Schmidtmann,
Sandie E. Dann,
Jenna L. Crisp,
Chick C. Wilson,
Mark T. Weller
,
Paul F. Henry,
Marc Schmidtmann,
Sandie E. Dann,
Jenna L. Crisp,
Chick C. Wilson,
Mark T. Weller
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Abstract
The hydrations of the excipients stable α-lactose (Lαs), with two particle sizes, and trehalose have been studied by neutron powder diffraction; analysis of the Avrami plots, derived from the bulk polycrystalline phase compositions, allows elucidation of the kinetics and mechanisms involved in these hydration processes.