Published in
Royal Society of Chemistry, Journal of Materials Chemistry B: Materials for biology and medicine, 44(4), p. 7080-7086
DOI: 10.1039/c6tb01272h
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Theranostic body fluid cleansing: rationally designed magnetic particles enable capturing and detection of bacterial pathogens
Journal article published in 2016 by
Marco Lattuada,
Q. Ren,
F. Zuber,
M. Galli,
N. Bohmer,
M. T. Matter 
,
A. Wichser,
S. Bertazzo,
G. B. Pier,
I. K. Herrmann
,
A. Wichser,
S. Bertazzo,
G. B. Pier,
I. K. Herrmann
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Abstract
We report on theoretical and experimental considerations on bacteria capturing and enrichment via magnetic separation enabling integrated diagnosis and treatment of blood stream infections. We show optimization of carrier-pathogen interactions based on a mathematical model followed by an experimental proof-of-concept study along with investigations on the process safety.