Personalized interventions that empower users through pertinent and reliable information alongside ubiquitous and user-friendly services can provide them with the opportunity of adopting healthy lifestyle choices which improve quality of life and help prevent a vast number of chronic diseases. The eServices for Life and Health research unit alongside the City of the Future Living Lab strives to apply an e-Service Design approach to deploy innovative ICT and multi-device based services, aimed at truly responding to user needs and aspirations – both inside and outside hospital walls.