Published in
Royal Society of Chemistry, Journal of Materials Chemistry B: Materials for biology and medicine, 20(4), p. 3584-3593, 2016
DOI: 10.1039/c5tb02747k
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Substrate Modulus Regulates Osteogenic Differentiation of Rat Mesenchymal Stem Cells through Integrin β1 and BMP Receptor Type IA
Journal article published in 2016 by
Ruijing Guo,
Sichang Lu,
Alyssa R. Merkel,
Julie A. Sterling,
Scott A. Guelcher 
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Abstract
Osteoblast differentiation of mesenchymal stem cells is regulated by both soluble factor (e.g., bone morphogenetic proteins (BMP)) and mechanically transduced signaling, but the mechanisms have only been partially elucidated.