Synthesis and evaluation of donepezil–ferulic acid hybrids as multi-target-directed ligands against Alzheimer's disease
Journal article published in 2016 by
Wei Xu,
Xiao-Bing Wang,
Zhi-Min Wang,
Jia Wu,
Fan Li,
Jin Wang,
Ling-Yi Kong
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Abstract
A novel family of donepezil–ferulic acid hybrids were designed, synthesized and biologically evaluated as multi-target-directed ligands against Alzheimer's disease by fusing a fragment of donepezil and ferulic acid.