Published in
Royal Society of Chemistry, MedChemComm, 4(6), p. 547-554
DOI: 10.1039/c4md00564c
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Beyond the affinity for protein kinase C: exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands
Journal article published in 2015 by
Daniela Rossi,
Virpi Talman,
Gustav Boije Af Gennäs,
Annamaria Marra,
Pietro Picconi,
Rita Nasti,
Massimo Serra 
,
Jihyae Ann,
Marialaura Amadio,
Alessia Pascale,
Raimo K. Tuominen,
Jari Yli-Kauhaluoma ,
Jeewoo Lee,
Simona Collina
,
Jihyae Ann,
Marialaura Amadio,
Alessia Pascale,
Raimo K. Tuominen,
Jari Yli-Kauhaluoma ,
Jeewoo Lee,
Simona Collina
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Abstract
Over the past fifteen years, we reported the design and synthesis of different series of compounds targeting the C1 domain of protein kinase C (PKC) that were based on various templates.