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Royal Society of Chemistry, Chemical Communications, 16(51), p. 3395-3398, 2015

DOI: 10.1039/c4cc10111a

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Unveiling the uncatalyzed reaction of alkynes with 1,2-dipoles for the room temperature synthesis of cyclobutenes

Journal article published in 2015 by Benito Alcaide, Pedro Almendros, Israel Fernández ORCID, Carlos Lázaro-Milla
This paper is available in a repository.
This paper is available in a repository.

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Abstract

2-(Pyridinium-1-yl)-1,1-bis(triflyl)ethanides have been used as 1,2-dipole precursors in a metal-free direct [2+2] cycloaddition reaction of alkynes. Remarkably, this mild and facile uncatalyzed protocol requires neither irradiation nor heating.