Published in
Royal Society of Chemistry, Chemical Communications, 9(51), p. 1591-1593
DOI: 10.1039/c4cc09205h
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Theonellasterone, a steroidal metabolite isolated from a Theonella sponge, protects peroxiredoxin-1 from oxidative stress reactions
Journal article published in 2015 by
L. Margarucci,
M. C. Monti,
A. Tosco,
R. Esposito,
A. Zampella 
,
V. Sepe,
M. Mozzicafreddo ,
R. Riccio,
A. Casapullo
,
V. Sepe,
M. Mozzicafreddo ,
R. Riccio,
A. Casapullo
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Abstract
Peroxiredoxin-1, a key enzyme in the cellular detoxification pathway, has been identified through a chemoproteomic approach as the main partner of theonellasterone, a marine bioactive metabolite.