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BioMed Central, Genome Biology, 1(10), p. 201

DOI: 10.1186/gb-2009-10-1-201

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Identifying protein-coding genes in genomic sequences

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Postprint: archiving allowed
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Abstract

Abstract The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets.