Published in
Royal Society of Chemistry, MedChemComm, 3(7), p. 512-518, 2016
DOI: 10.1039/c5md00443h
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Drug trapping in hERG K + channels: (not) a matter of drug size?
Journal article published in 2016 by
Tobias Linder,
Harald Bernsteiner,
Priyanka Saxena,
Florian Bauer,
Thomas Erker,
Eugen Timin,
Steffen Hering,
Anna Stary-Weinzinger 
This paper is made freely available by the publisher.
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Abstract
The hERG cavity can trap very bulky compounds, without perturbing normal gate closure.