Published in
Royal Society of Chemistry, Chemical Communications, 16(52), p. 3380-3383, 2016
DOI: 10.1039/c6cc00160b
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The Evans Aldol–Prins cyclization: a general and stereoselective method for the synthesis of 2,3,4,5,6-pentasubstituted tetrahydropyrans
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Abstract
A method for the synthesis of 2,3,4,5,6-pentasubstituted THPs with good yields and diastereoselectivities through an Evans Aldol–Prins strategy is described.