Published in
Royal Society of Chemistry, New Journal of Chemistry, 12(39), p. 9171-9180, 2015
DOI: 10.1039/c5nj01149c
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Studies on the reactions between the DNA bases and a model α,β-unsaturated oxoaldehyde
Journal article published in 2015 by
Donata Pluskota-Karwatka,
Malwina Muńko,
Marcin Hoffmann 
,
Martyna Kuta,
Leif Kronberg
,
Martyna Kuta,
Leif Kronberg
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Abstract
Two sets of adducts of 2′-dC with a model oxoenal were characterised based on 2D NMR spectroscopy. DFT calculations indicated that two mechanisms can be involved in these compounds formation. The instability of one of these products leads to deamination of 2′-dC.