Published in

Royal Society of Chemistry, Journal of Materials Chemistry B: Materials for biology and medicine, 7(4), p. 1337-1342, 2016

DOI: 10.1039/c5tb02726h

Links

Tools

Export citation

Search in Google Scholar

Ruthenium(II) Complex-Photosensitized Multifunctionalized Porous Silicon Nanoparticles for Two-Photon Near-Infrared Light Responsive Imaging and Photodynamic Cancer Therapy

Journal article published in 2016 by Nikola Ž. Knezevic, Vanja Stojanovic, Arnaud Chaix, Elise Bouffard, Khaled El Cheikh, Alain Morère, Marie Maynadier, Gilles Lemercier, Marcel Garcia, Magali Gary-Bobo, Jean-Olivier Durand, Frederique Cunin ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Multifunctionalized porous silicon nanoparticles (pSiNP) containing novel Ru(II) complex-photosensitizer, polyethylene glycol moiety, and mannose molecules as cancer targeting ligands, are constructed and showcased for application in near infrared (NIR) light-responsive photodynamic therapy (PDT) and imaging of cancer. Exposure to NIR light leads to two-photon excitation of the Ru(II)-complex which allows efficient simultaneous cancer-imaging and targeted PDT therapy with the functionalized biodegradable pSiNP nanocarriers.