The combined effect of anthocyanin-flavanol-flavonol ternary interactions on the colorimetric and chemical stability of malvidin 3-glucoside has been studied. Model solutions with fixed malvidin 3-glucoside:(+)-catechin ratio (MC) and variable quercetin-3-β-D-glucoside concentration (MC+Q), and solutions with fixed malvidin 3-glucoside:quercetin-3-β-D-glucoside ratio (MQ) and variable (+)-catechin concentration (MQ+C) were tested at levels closer to those existing in wines. Color variations during storage were evaluated by Differential Colorimetry. Changes in the anthocyanin concentration were monitored by HPLC-DAD. CIELAB color-difference formulas demonstrated to be of practical interest to assess the stronger and more stable interaction of quercetin-3-β-D-glucoside with MC binary mixture than (+)-catechin with MQ mixture. Results imply that MC+Q ternary solutions kept their intensity and bluish tonalities for a longer time in comparison to MQ+C solutions. The stability of malvidin 3-glucoside improves when the concentration of quercetin-3-β-D-glucoside increases in MC+Q mixtures while the addition of (+)-catechin in MQ+C mixtures resulted in an opposite effect.