Published in
Royal Society of Chemistry, MedChemComm, 9(6), p. 1656-1665, 2015
DOI: 10.1039/c5md00259a
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Novel peptidomimetics related to gonadotropin-releasing hormone (GnRH)
Journal article published in 2015 by
Arianna Gelain,
Luca Rizzi,
Laura Legnani,
Aurora Pacini,
Katerina Spyridaki,
Vlasios Karageorgos,
George Liapakis,
Stefania Villa
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Abstract
Novel GnRH I and II analogues were designed and synthesized by Solid Phase Peptides Synthesis (SPPS), since GnRH has antiproliferative properties, but poor metabolic stability.