Published in

Royal Society of Chemistry, MedChemComm, 2(2), p. 132-139

DOI: 10.1039/c0md00200c

Links

Tools

Export citation

Search in Google Scholar

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2). Identification and synthesis of N-propyl-5-substituted isoquinolones

Journal article published in 2011 by Andrés A. Trabanco ORCID, Guillaume Duvey, José María Cid, Gregor J. Macdonald, Philippe Cluzeau, Vanthea Nhem, Rocco Furnari, Nadia Behaj, Géraldine Poulain, Terry Finn, Sonia Poli, Hilde Lavreysen, Alexandre Raux, Yves Thollon, Nicolas Poirier and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

N-propyl-5-substituted isoquinolones were identified as mGluR2 PAMs via high-throughput screening (HTS). Initial SAR exploration led to the identification of compound 20.