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Royal Society of Chemistry, Chemical Communications, 5, p. 597-599, 2009

DOI: 10.1039/b816550e

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Synergic asymmetric organocatalysis (SAOc) of Cinchonaalkaloids and secondary amines in the synthesis of bicyclo[2.2.2]octan-2-ones

Journal article published in 2009 by Marco Bella, Daniele M. Scarpino Schietroma, Pier Paolo Cusella, Tecla Gasperi ORCID, Valerio Visca
This paper is available in a repository.
This paper is available in a repository.

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Abstract

A synergistic effect between chiral secondary and tertiary amines gives access to bicyclo[2.2.2]octan-2-ones with up to 90% ee and >10 : 1 dr.