Published in
Royal Society of Chemistry, Analyst, 7(139), p. 1609
DOI: 10.1039/c3an02262e
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In situ molecular imaging of a hydrated biofilm in a microfluidic reactor by ToF-SIMS
Journal article published in 2014 by
Xin Hua,
Xiao-Ying Yu 
,
Zhaoying Wang,
Li Yang,
Bingwen Liu,
Zihua Zhu,
Abigail E. Tucker,
William B. Chrisler,
Eric A. Hill,
Theva Thevuthasan,
Yuehe Lin,
Songqin Liu,
Matthew J. Marshall
,
Zhaoying Wang,
Li Yang,
Bingwen Liu,
Zihua Zhu,
Abigail E. Tucker,
William B. Chrisler,
Eric A. Hill,
Theva Thevuthasan,
Yuehe Lin,
Songqin Liu,
Matthew J. Marshall
This paper is available in a repository.
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Abstract
A novel microfluidic reactor for biofilm growth and in situ characterization using time-of-flight secondary ion mass spectrometry (ToF-SIMS) was constructed to enable two-dimensional chemical imaging of hydrated biofilms. We demonstrate the detection of characteristic fatty acid fragments from microfluidic reactor-grown biofilms and illustrate advantages of hydrated-state ToF-SIMS imaging.