A screening of Pd/zeolite-based catalysts in the PrOx-CO reaction in H2-rich streams was performed using zeolites with different cations (H+, Na+ and Cs+) prepared by ion exchange and framework type (MFI and FAU). The assessment of the catalytic performance displayed by these zeolite-based samples revealed that both parameters play an important role in the catalytic behaviour. The optimisation of both parameters led to the preparation of an optimum catalyst, which showed high CO conversion and CO selectivity during long-term stability tests. ; The authors thank the Spanish MINECO, GV and FEDER (PROMETEOII/2014/010, Projects CTQ2012-31762), for financial support.