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Royal Society of Chemistry, Chemical Communications, 1(48), p. 79-81

DOI: 10.1039/c1cc16014a

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Productivity enhancement of C=C bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes

Journal article published in 2011 by M. Elisabetta Brenna, Francesco G. Gatti, Daniela Monti ORCID, Fabio Parmeggiani, Alessandro Sacchetti
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

To overcome the usually low productivities of the C=C bond bioreduction of α,β-unsaturated aldehydes we combined the in situ substrate feeding product removal (SFPR) technology with a cascade system comprising an isolated ene-reductase and a chemoselective alcohol dehydrogenase.