Published in
Royal Society of Chemistry, Chemical Communications, 98(49), p. 11542, 2013
DOI: 10.1039/c3cc47171c
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Hypervalent iodine-mediated oxidative cyclisation of p-hydroxy acetanilides to 1,2-dispirodienones
Journal article published in 2013 by
Laurent Chabaud,
Tatiana Hromjakova,
Matt Rambla,
Pascal Retailleau,
Catherine Guillou 
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Abstract
1,2-Dispirodienones were synthesized by hypervalent iodine-mediated phenolic oxidation of p-hydroxy acetanilides. The reaction is compatible with several substituted anilides and affords a new class of 1,2-dispirodienones that are remarkably stable under thermal or acidic conditions.