A new dual-boron-cored luminogen ligated with nitrogen-containing multidentate ligand and four bulky phenyl rings, was readily synthesized. The unique molecular structure renders this BN-containing luminogen with rich photophysical properties in either solution or in solid state, including a large Stokes shift, aggregation induced emission activity and reversible piezochromism. Furthermore, this BN-containing luminogen exhibits good capabilities for imaging living cells and sensing of fluoride anion.