Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 4(10), p. 825-834
DOI: 10.1039/c1ob06374j
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A formal [3+3]-annulation-based approach to pancratistatins: Total synthesis of (±)-7-deoxy-pancratistatin and its 2-epi and 2,4-diepi analogues
Journal article published in 2011 by
Olaia Nieto-García,
Hugo Lago-Santomé,
Fernando Cagide-Fagín 
,
Juan Carlos Ortiz-Lara,
Ricardo Alonso
,
Juan Carlos Ortiz-Lara,
Ricardo Alonso
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Abstract
A full account is given for the total synthesis and the cytotoxic activity against the human lung tumoral cell line NCI-H460 of (±)-7-deoxy-pancratistatin and its 2-epi- and 2,4-diepi- unnatural analogues.