Published in
Elsevier, Biophysical Journal, 3(100), p. 522a, 2011
DOI: 10.1016/j.bpj.2010.12.3050
Royal Society of Chemistry, Lab on a Chip, 24(10), p. 3373
DOI: 10.1039/c0lc00376j
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Interfacial tension controlled fusion of individual femtolitre droplets and triggering of confined chemical reactions on demand
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Abstract
This paper describes stepwise on-demand generation and fusion of femtolitre aqueous droplets based on interfacial tension. Sub-millisecond reaction times from droplet fusion were demonstrated, as well as a reversible chemical toggle switch based on alternating fusion of droplets containing acidic or basic solution, monitored with the pH-dependent emission of fluorescein.