Royal Society of Chemistry, Chemical Communications, 79(50), p. 11694-11697
DOI: 10.1039/c4cc03897e
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Based on electronic structure calculations we propose that particular small-sized organic molecules - donor-acceptor substituted phenyl polymethines -can be used as two-photon diagnostic probes for non-invasive imaging of amyloid oligomers and fibrils which are often referred to as the ``early signature'' of Alzheimer's disease.