Published in

Royal Society of Chemistry, Chemical Communications, 31(51), p. 6777-6780

DOI: 10.1039/c5cc01412c

Links

Tools

Export citation

Search in Google Scholar

Rh/Cu-catalyzed multiple C–H, C–C, and C–N bond cleavage: facile synthesis of pyrido[2,1-a]indoles from 1-(pyridin-2-yl)-1H-indoles and γ-substituted propargyl alcohols

Journal article published in 2015 by Ting Li, Zhen Wang ORCID, Mingliang Zhang, Hui-Jun Zhang ORCID, Ting-Bin Wen ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

An unusual Rh/Cu-catalyzed synthesis of pyrido[2,1-a]indoles starting from 1-(pyridin-2-yl)-1H-indoles and γ-substituted propargyl alcohols was presented. The multi-step cascade transformations formally involve the cleavage of two C-H, three C-C, and one C-N bonds with concomitant construction of two C-H, four C-C, and one C-N bonds with excellent chemoselectivity in one-pot reaction.