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Wiley-VCH Verlag, ChemInform, 2(44), p. no-no, 2013

DOI: 10.1002/chin.201302174

Royal Society of Chemistry, Chemical Communications, 74(48), p. 9310

DOI: 10.1039/c2cc33511e

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Synthesis and biological evaluation of unprecedented ring-expanded nucleosides (RENs) containing the imidazo[4,5-d][1,2,6]oxadiazepine ring system

Journal article published in 2012 by Stefano D'Errico, Giorgia Oliviero, Jussara Amato, Nicola Borbone, Vincenzo Cerullo, Akseli Hemminki, Vincenzo Piccialli, Sabrina Zaccaria, Luciano Mayol ORCID, Gennaro Piccialli ORCID
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This paper is available in a repository.

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Abstract

A small collection of ring-expanded nucleosides (RENs), containing the unprecedented bis-alkylated imidazo[4,5-d][1,2,6]oxadiazepine heterocyclic ring system, has been synthesized through a new general approach. Results of preliminary cytotoxicity tests on breast (MCF-7) and lung (A549) cancer cell lines are also reported.