Wiley-VCH Verlag, ChemInform, 2(44), p. no-no, 2013
Royal Society of Chemistry, Chemical Communications, 74(48), p. 9310
DOI: 10.1039/c2cc33511e
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A small collection of ring-expanded nucleosides (RENs), containing the unprecedented bis-alkylated imidazo[4,5-d][1,2,6]oxadiazepine heterocyclic ring system, has been synthesized through a new general approach. Results of preliminary cytotoxicity tests on breast (MCF-7) and lung (A549) cancer cell lines are also reported.