Cambridge University Press, Infection Control and Hospital Epidemiology, 4(27), p. 413-415
DOI: 10.1086/503175
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To better determine the optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection, we evaluated the utility of a novel combination antibiogram. Although the combination antibiogram allowed modest fine-tuning of choices for dual antibiotic therapy, selections based on the 2 antibiograms did not differ substantively. Drug combinations with the broadest coverage were consistently composed of an aminoglycoside and a β-lactam. © 2006 by The Society for Healthcare Epidemiology of America. All rights reserved.