Published in
Royal Society of Chemistry, Lab on a Chip, 15(13), p. 2879, 2013
DOI: 10.1039/c3lc41343h
Links
- ORCID
- Royal Society of Chemistry
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
Tools
Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles
Journal article published in 2013 by
Zongxing Wang,
Hung-Jen Wu,
Daniel Fine,
Jeffrey Schmulen,
Ye Hu,
Biana Godin 
,
John X. J. Zhang,
Xuewu Liu
,
John X. J. Zhang,
Xuewu Liu
This paper is available in a repository.
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Abstract
We fabricated a microfluidic device consisting of ciliated micropillars, forming a porous silicon nanowire-on-micropillar structure. We demonstrated that the prototype device can preferentially trap exosome-like lipid vesicles, while simultaneously filtering out proteins and cell debris. Trapped lipid vesicles can be recovered intact by dissolving the porous nanowires in PBS buffer.