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Royal Society of Chemistry, Molecular BioSystems, 3(7), p. 714, 2011

DOI: 10.1039/c0mb00217h

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The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives

Journal article published in 2011 by Yane-Shih Wang ORCID, William K. Russell, Zhiyong Wang, Wei Wan, Lindsey E. Dodd, Pei-Jing Pai, David H. Russell, Wenshe R. Liu
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Using evolved pyrrolysyl-tRNA synthetase-tRNA(CUA)(Pyl) pairs, L-phenylalanine, p-iodo-L-phenylalanine and p-bromo-L-phenylalanine have been genetically incorporated into proteins at amber mutation sites in E. coli.