Royal Society of Chemistry, Lab on a Chip, 6(15), p. 1445-1450, 2015
DOI: 10.1039/c4lc01451k
Full text: Unavailable
We developed a novel gradient generator to achieve long range and linear chemical gradient with dynamic control function. The length of the gradient can be at centimetre scale. The gradient profile can be tuned by changing the flow rates. The device can work in both high flow rate regime with large shear stress and low flow rate with minimum shear stress. The function of drug screening is demonstrated by the viability test of PC-9 cancer cells.