Royal Society of Chemistry, Chemical Communications, 46(51), p. 9475-9478
DOI: 10.1039/c5cc03052h
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Glycation and its products cause a host of pathological conditions but their exact roles are yet to be determined. Pyrraline, a key product of glycation, and a novel pyrraline-derived cross-link have been incorporated into collagenous peptides via Maillard condensations performed on resin-bound peptide sequences.